Eps15l1 | epidermal growth factor receptor pathway substrate 15-like 1
Physiological systems
17 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Adipose tissue Vision/eye Hematopoietic system Behavior/neurological
12 No significant impact
7 Not tested
Data collections
Gene metrics:7Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased total body fat amount | 1 supporting dataset | Eps15l1em1(IMPC)J | homozygote | Early adult | 9.53x10-5 | ||
| hyperactivity | 8 supporting datasets | Eps15l1em1(IMPC)J | homozygote | Early adult | 3.28x10-26 | ||
| irregularly shaped pupil | 1 supporting dataset | Eps15l1em1(IMPC)J | homozygote | Early adult | 2.03x10-5 | ||
| increased mean corpuscular volume | 1 supporting dataset | Eps15l1em1(IMPC)J | homozygote | Early adult | 3.69x10-6 | ||
| increased mean corpuscular hemoglobin | 1 supporting dataset | Eps15l1em1(IMPC)J | homozygote | Early adult | 2.19x10-8 | ||
| abnormal vocalization | 1 supporting dataset | Eps15l1em1(IMPC)J | homozygote | Early adult | 2.94x10-10 | ||
| increased circulating alkaline phosphatase level | 1 supporting dataset | Eps15l1em1(IMPC)J | homozygote | Early adult | 1.27x10-13 |
| | | | | | | | | | |
External links
No external links available for Eps15l1.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
| Eps15l1em1(IMPC)J | Exon Deletion | | mouse |
| Eps15l1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Eps15l1tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | ES Cell |