Rapgef1 | Rap guanine nucleotide exchange factor (GEF) 1

GeneMGI:104580Synonyms: C3G, 4932418O06Rik, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Mortality/aging

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:48Adult tissues

25Embryo tissues

Phenotypes

Zygosity:

Phy. System:



abnormal retina morphology	1 supporting dataset	Rapgef1^{tm1b(KOMP)Wtsi}	heterozygote	Early adult	6.17x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Rapgef1^{tm1b(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Rapgef1.

Associated images

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Histopathology

There is no histopathology data found for Rapgef1.

IMPC related publications

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External links

No external links available for Rapgef1.

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*Rapgef1^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Rapgef1^{tm1b(KOMP)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Rapgef1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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