Napa | N-ethylmaleimide sensitive fusion protein attachment protein alpha

GeneMGI:104563Synonyms: hyh, SNAPA, +4 more

Physiological systems

21 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Immune system Integument Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological

15 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal skin morphology2 supporting datasetsNapaem1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal spleen morphology2 supporting datasetsNapaem1(IMPC)CcpczheterozygoteEarly adultN/A * 
abnormal behavior1 supporting datasetNapaem1(IMPC)CcpczheterozygoteEarly adult2.81x10-5 
abnormal lens morphology1 supporting datasetNapaem1(IMPC)CcpczheterozygoteEarly adult5.39x10-5 
abnormal startle reflex1 supporting datasetNapaem1(IMPC)CcpczheterozygoteEarly adult4.81x10-9 
enlarged spleen1 supporting datasetNapaem1(IMPC)CcpczheterozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Napaem1(IMPC)CcpczExon Deletionmouse
Napatm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Napatm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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