Gcdh | glutaryl-Coenzyme A dehydrogenase

GeneMGI:104541Synonyms: D17825

Physiological systems

12 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Cardiovascular system Mortality/aging

10 No significant impact

12 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

2Associated diseases

Expression examined in:51Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



preweaning lethality, incomplete penetrance	1 supporting dataset	Gcdh^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased heart left ventricle size	1 supporting dataset	Gcdh^{tm2b(EUCOMM)Hmgu}	homozygote	Early adult	1.37x10^-7

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Gcdh.

Associated images

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Histopathology

There is no histopathology data found for Gcdh.

IMPC related publications

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External links

No external links available for Gcdh.

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*Gcdh^{em1(IMPC)Hmgu}*	Exon Deletion	‌	mouse
*Gcdh^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Gcdh^{tm2b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Gcdh^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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