Adsl | adenylosuccinate lyase
GeneMGI:103202
Physiological systems
20 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Vision/eye Cardiovascular system Mortality/aging
17 No significant impact
4 Not tested
Data collections
Gene metrics:6Significant phenotypes
2Associated diseases
Expression examined in:49Adult tissues
62Embryo tissues
| preweaning lethality, complete penetrance | 3 supporting datasets | Adsltm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal retina blood vessel morphology | 1 supporting dataset | Adsltm1b(KOMP)Wtsi | heterozygote | Early adult | 3.27x10-5 | ||
| abnormal retina vasculature morphology | 1 supporting dataset | Adsltm1b(KOMP)Wtsi | heterozygote | Early adult | 5.36x10-6 | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Adsltm1b(KOMP)Wtsi | homozygote | E9.5 | N/A * | ||
| abnormal retina morphology | 1 supporting dataset | Adsltm1b(KOMP)Wtsi | heterozygote | Early adult | 3.51x10-7 | ||
| microphthalmia | 1 supporting dataset | Adsltm1b(KOMP)Wtsi | heterozygote | Early adult | N/A * |
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External links
No external links available for Adsl.
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| Adsltm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Adsltm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |