Zfp354a | zinc finger protein 354A

GeneMGI:103172Synonyms: kid1, Tcf17

Physiological systems

20 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Renal/urinary system

15 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged kidney1 supporting datasetZfp354aem1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged lymph nodes1 supporting datasetZfp354aem1(IMPC)MbphomozygoteEarly adultN/A * 
enlarged spleen1 supporting datasetZfp354aem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal spleen morphology1 supporting datasetZfp354aem1(IMPC)MbphomozygoteEarly adultN/A * 
abnormal lymph node morphology1 supporting datasetZfp354aem1(IMPC)MbphomozygoteEarly adultN/A * 
increased circulating creatinine level1 supporting datasetZfp354aem1(IMPC)MbphomozygoteEarly adult3.84x10-6 
abnormal kidney morphology1 supporting datasetZfp354aem1(IMPC)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Zfp354aem1(IMPC)MbpExon Deletionmouse
Zfp354atm44235(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Zfp354atm44235(L1L2_gt1)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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