Slc12a1 | solute carrier family 12, member 1
Physiological systems
14 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Hematopoietic system
11 No significant impact
10 Not tested
Data collections
Gene metrics:8Significant phenotypes
1Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| decreased body weight | 3 supporting datasets | Slc12a1urehr3 | homozygote | Early adult | 8.05x10-6 | ||
| increased blood urea nitrogen level | 1 supporting dataset | Slc12a1urehr3 | homozygote | Early adult | 8.41x10-33 | ||
| increased circulating creatinine level | 1 supporting dataset | Slc12a1urehr3 | homozygote | Early adult | 2.21x10-8 | ||
| increased circulating amylase level | 1 supporting dataset | Slc12a1urehr3 | homozygote | Early adult | 1.9x10-9 | ||
| decreased circulating chloride level | 1 supporting dataset | Slc12a1urehr3 | homozygote | Early adult | 1.43x10-11 | ||
| increased circulating calcium level | 1 supporting dataset | Slc12a1urehr3 | homozygote | Early adult | 1.4x10-7 | ||
| decreased hematocrit | 1 supporting dataset | Slc12a1urehr3 | homozygote | Early adult | 9.19x10-5 | ||
| decreased hemoglobin content | 1 supporting dataset | Slc12a1urehr3 | homozygote | Early adult | 4.36x10-5 |
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External links
No external links available for Slc12a1.
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| Slc12a1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |