F10 | coagulation factor X
Physiological systems
20 / 24 physiological systems tested
5 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Behavior/neurological Mortality/aging Renal/urinary system
15 No significant impact
4 Not tested
Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| preweaning lethality, complete penetrance | 1 supporting dataset | F10tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| decreased circulating creatinine level | 1 supporting dataset | F10tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 6.56x10-5 | ||
| increased kidney weight | 1 supporting dataset | F10tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 7.47x10-5 | ||
| increased grip strength | 1 supporting dataset | F10tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 4.8x10-5 |
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External links
No external links available for F10.
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| F10tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| F10tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| F10tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |