Anapc1 | anaphase promoting complex subunit 1

GeneMGI:103097Synonyms: Apc1, tsg24, +2 more

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Vision/eye Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



increased circulating alkaline phosphatase level	1 supporting dataset	Anapc1^em1(IMPC)J	heterozygote	Early adult	1.08x10^-5
preweaning lethality, complete penetrance	1 supporting dataset	Anapc1^em1(IMPC)J	homozygote	Early adult	N/A ^*
abnormal lens morphology	1 supporting dataset	Anapc1^em1(IMPC)J	heterozygote	Late adult	8.18x10^-7
embryonic lethality prior to organogenesis	1 supporting dataset	Anapc1^em1(IMPC)J	homozygote	E9.5	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Anapc1.

Associated images

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Histopathology

There is no histopathology data found for Anapc1.

IMPC related publications

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External links

No external links available for Anapc1.

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*Anapc1^em1(IMPC)J*	Exon Deletion	‌	mouse
*Anapc1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Anapc1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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