Il15 | interleukin 15

GeneMGI:103014

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Behavior/neurological Cardiovascular system

15 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

0Associated diseases

Expression examined in:46Adult tissues

42Embryo tissues

Phenotypes

Phy. System:



limb grasping	1 supporting dataset	Il15^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.62x10^-11
enlarged heart	1 supporting dataset	Il15^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased grip strength	1 supporting dataset	Il15^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	6.4x10^-5
impaired glucose tolerance	1 supporting dataset	Il15^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	2.3x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Il15.

Associated images

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Histopathology

There is no histopathology data found for Il15.

IMPC related publications

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External links

No external links available for Il15.

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*Il15^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Il15^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Il15^{tm1c(EUCOMM)Hmgu}*	Wild type floxed exon (post-Flp)	‌	mouse

My Genes