Epb41l5 | erythrocyte membrane protein band 4.1 like 5

GeneMGI:103006Synonyms: Lulu1, NBL5, +3 more

Physiological systems

19 / 24 physiological systems tested

5 Significantly impacted by the knock-out

 Growth/size/body region Vision/eye Hematopoietic system Behavior/neurological Cardiovascular system

14 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

increased startle reflex1 supporting datasetEpb41l5tm1a(EUCOMM)HmguheterozygoteEarly adult3.57x10-6 
abnormal retina morphology3 supporting datasetsEpb41l5tm1a(EUCOMM)HmguheterozygoteEarly adult1.58x10-5 
increased mean corpuscular volume1 supporting datasetEpb41l5tm1a(EUCOMM)HmguheterozygoteEarly adult6.47x10-5 
increased lean body mass1 supporting datasetEpb41l5tm1a(EUCOMM)HmguheterozygoteEarly adult5.63x10-6 
increased heart weight1 supporting datasetEpb41l5tm1a(EUCOMM)HmguheterozygoteEarly adult6.41x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Epb41l5tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Epb41l5tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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