Vcan | versican

GeneMGI:102889Synonyms: DPEAAE, PG-M, +4 more

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Immune system Embryo Growth/size/body region Nervous system Vision/eye Hematopoietic system Mortality/aging Cardiovascular system Craniofacial

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:20Significant phenotypes

2Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal heart morphology	1 supporting dataset	Vcan^em2(IMPC)Mbp	heterozygote	E9.5	N/A ^*
abnormal placenta morphology	1 supporting dataset	Vcan^em2(IMPC)Mbp	heterozygote	E15.5	N/A ^*
abnormal optic vesicle formation	1 supporting dataset	Vcan^em2(IMPC)Mbp	homozygote	E9.5	N/A ^*
abnormal vitelline vasculature morphology	1 supporting dataset	Vcan^em2(IMPC)Mbp	homozygote	E9.5	N/A ^*
microphthalmia	1 supporting dataset	Vcan^em2(IMPC)Mbp	heterozygote	E15.5	N/A ^*
abnormal embryo turning	1 supporting dataset	Vcan^em2(IMPC)Mbp	homozygote	E9.5	N/A ^*
abnormal visceral yolk sac morphology	1 supporting dataset	Vcan^em2(IMPC)Mbp	homozygote	E9.5	N/A ^*
enlarged spleen	1 supporting dataset	Vcan^em2(IMPC)Mbp	heterozygote	Early adult	N/A ^*
preweaning lethality, complete penetrance	1 supporting dataset	Vcan^em2(IMPC)Mbp	homozygote	Early adult	N/A ^*
persistence of hyaloid vascular system	1 supporting dataset	Vcan^em2(IMPC)Mbp	heterozygote	Early adult	1.27x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Vcan.

Associated images

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Histopathology

There is no histopathology data found for Vcan.

IMPC related publications

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External links

No external links available for Vcan.

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*Vcan^em1H*	Point Mutation	‌	mouse
*Vcan^em2(IMPC)Mbp*	Exon Deletion	‌	mouse
*Vcan^em2H*	Point Mutation	‌	mouse
*Vcan^tm1(KOMP)Mbp*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector ES Cell
*Vcan^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Vcan^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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