Pdx1 | pancreatic and duodenal homeobox 1

GeneMGI:102851Synonyms: Ipf1, IDX-1, +4 more

Physiological systems

21 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Mortality/aging

19 No significant impact

3 Not tested

Gene metrics:2Significant phenotypes
6Associated diseases
Expression examined in:51Adult tissues
62Embryo tissues

Phenotypes

preweaning lethality, complete penetrance3 supporting datasetsPdx1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
impaired glucose tolerance1 supporting datasetPdx1tm1b(EUCOMM)WtsiheterozygoteEarly adult3.67x10-14 
* Does not have a P-value assigned because it was manually marked as significant.
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* Does not have a P-value assigned because it was manually marked as significant.
Download data as:  

lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Pdx1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Pdx1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Pdx1tm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell

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