Entpd1 | ectonucleoside triphosphate diphosphohydrolase 1

GeneMGI:102805Synonyms: ectoapyrase, 2610206B08Rik, +2 more

Physiological systems

22 / 24 physiological systems tested

6 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Growth/size/body region Hematopoietic system Behavior/neurological Skeleton

16 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

2Associated diseases

Expression examined in:70Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Allele:

Phy. System:



increased lean body mass	1 supporting dataset	Entpd1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.29x10^-6
increased circulating chloride level	1 supporting dataset	Entpd1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	9.04x10^-6
decreased grip strength	2 supporting datasets	Entpd1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	5.76x10^-9
increased bone mineral content	1 supporting dataset	Entpd1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.8x10^-6
increased IgE level	1 supporting dataset	Entpd1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	2.87x10^-6
decreased circulating glycerol level	1 supporting dataset	Entpd1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.14x10^-5
increased circulating sodium level	1 supporting dataset	Entpd1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.2x10^-6
tremors	1 supporting dataset	Entpd1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	8.05x10^-6
abnormal bone mineralization	1 supporting dataset	Entpd1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	4.23x10^-5
thrombocytopenia	1 supporting dataset	Entpd1^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	9.86x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Entpd1.

Associated images

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Histopathology

There is no histopathology data found for Entpd1.

IMPC related publications

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External links

No external links available for Entpd1.

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*Entpd1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Entpd1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Entpd1^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Entpd1^{tm47236(L1L2_st0)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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