Fstl1 | follistatin-like 1

GeneMGI:102793Synonyms: TSC-36

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Immune system Hematopoietic system

16 No significant impact

5 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues

Phenotypes

increased circulating cholesterol level1 supporting datasetFstl1tm1b(EUCOMM)HmguhomozygoteEarly adult1.67x10-5 
increased lymphocyte cell number1 supporting datasetFstl1tm1b(EUCOMM)HmguhomozygoteEarly adult2.05x10-5 
decreased fasting circulating glucose level1 supporting datasetFstl1tm1b(EUCOMM)HmguhomozygoteEarly adult4.44x10-5 
decreased neutrophil cell number1 supporting datasetFstl1tm1b(EUCOMM)HmguhomozygoteEarly adult3.16x10-5 
impaired glucose tolerance1 supporting datasetFstl1tm1b(EUCOMM)HmguhomozygoteEarly adult2.63x10-5 
increased circulating HDL cholesterol level1 supporting datasetFstl1tm1b(EUCOMM)HmguhomozygoteEarly adult4.06x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Fstl1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)es cell
Fstl1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Fstl1tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Fstl1tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell

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