Aimp1 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

GeneMGI:102774Synonyms: Emap2, 9830137A06Rik, +3 more

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Embryo Growth/size/body region Hematopoietic system Mortality/aging

13 No significant impact

4 Not tested

Gene metrics:10Significant phenotypes
3Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance3 supporting datasetsAimp1em1(IMPC)TcphomozygoteEarly adultN/A * 
abnormal embryo size1 supporting datasetAimp1em1(IMPC)TcphomozygoteE18.5N/A * 
absent seminal vesicle1 supporting datasetAimp1em1(IMPC)TcphomozygoteEarly adultN/A * 
hydrometra1 supporting datasetAimp1em1(IMPC)TcphomozygoteEarly adultN/A * 
enlarged spleen2 supporting datasetsAimp1em1(IMPC)TcphomozygoteEarly adultN/A * 
male infertility1 supporting datasetAimp1em1(IMPC)TcphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Aimp1em1(IMPC)TcpExon Deletionmouse
Aimp1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Aimp1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Aimp1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Aimp1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell
Aimp1tm2a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Aimp1tm2e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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