Cdc34 | cell division cycle 34

GeneMGI:102657Synonyms: UBE2R1

Physiological systems

19 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Integument Mortality/aging

15 No significant impact

5 Not tested

Gene metrics:4Significant phenotypes
0Associated diseases
Expression examined in:49Adult tissues
50Embryo tissues

Phenotypes

abnormal nail morphology1 supporting datasetCdc34tm1.1(KOMP)MbpheterozygoteEarly adult4.69x10-5 
increased fasting circulating glucose level1 supporting datasetCdc34tm1.1(KOMP)MbpheterozygoteEarly adult8.27x10-5 
preweaning lethality, incomplete penetrance1 supporting datasetCdc34tm1.1(KOMP)MbphomozygoteEarly adultN/A * 
male infertility1 supporting datasetCdc34tm1.1(KOMP)MbphomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cdc34tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
mouse
Cdc34tm1.1(KOMP)MbpReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Cdc34tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell
Cdc34tm437830(L1L2_GT0_LF2A_LacZ_BetactP_neo)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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