Nfatc1 | nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

GeneMGI:102469Synonyms: NF-ATc, NFAT2, +2 more

Physiological systems

16 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Behavior/neurological Mortality/aging

14 No significant impact

8 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



decreased locomotor activity	1 supporting dataset	Nfatc1^em1(IMPC)Bay	heterozygote	Early adult	6.01x10^-5
preweaning lethality, complete penetrance	3 supporting datasets	Nfatc1^em1(IMPC)Bay	homozygote	Early adult	N/A ^*
abnormal locomotor behavior	1 supporting dataset	Nfatc1^em1(IMPC)Bay	heterozygote	Early adult	3.36x10^-8

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nfatc1.

Associated images

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Histopathology

There is no histopathology data found for Nfatc1.

IMPC related publications

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External links

No external links available for Nfatc1.

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*Nfatc1^em1(IMPC)Bay*	Point Mutation	‌	mouse
*Nfatc1^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Nfatc1^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

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