Thpo | thrombopoietin
Physiological systems
21 / 24 physiological systems tested
6 Significantly impacted by the knock-out
Homeostasis/metabolism Vision/eye Respiratory system Hematopoietic system Skeleton Craniofacial
15 No significant impact
3 Not tested
Data collections
Gene metrics:7Significant phenotypes
7Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues
decreased pulmonary ventilation | 2 supporting datasets | Thpotm1.1(KOMP)Vlcg | homozygote | Early adult | 1.41x10-12 | ||
decreased bronchoconstrictive response | 1 supporting dataset | Thpotm1.1(KOMP)Vlcg | homozygote | Early adult | 2.54x10-7 | ||
thrombocytopenia | 1 supporting dataset | Thpotm1.1(KOMP)Vlcg | homozygote | Early adult | 3.63x10-6 | ||
increased mean platelet volume | 1 supporting dataset | Thpotm1.1(KOMP)Vlcg | homozygote | Early adult | 3.21x10-6 | ||
abnormal cranium morphology | 1 supporting dataset | Thpotm1.1(KOMP)Vlcg | homozygote | Early adult | 1.74x10-5 | ||
cornea opacity | 1 supporting dataset | Thpotm1.1(KOMP)Vlcg | homozygote | Early adult | 8.45x10-5 | ||
increased pulmonary respiratory rate | 1 supporting dataset | Thpotm1.1(KOMP)Vlcg | homozygote | Early adult | 9.79x10-6 |
| | | | | | | | | |
External links
No external links available for Thpo.
All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.
Thpotm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | ES Cell mouse |
Thpotm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
Thpotm1.1(KOMP)Vlcg | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
Thpotm2(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |