Gys1 | glycogen synthase 1, muscle

GeneMGI:101805Synonyms: Gys3, MGS

Physiological systems

17 / 24 physiological systems tested

6 Significantly impacted by the knock-out

 Homeostasis/metabolism Integument Embryo Growth/size/body region Skeleton Mortality/aging

11 No significant impact

7 Not tested

Gene metrics:7Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal skin coloration1 supporting datasetGys1em1(IMPC)BayhomozygoteE18.5N/A * 
abnormal embryo size1 supporting datasetGys1em1(IMPC)BayhomozygoteE18.5N/A * 
edema1 supporting datasetGys1em1(IMPC)BayhomozygoteE18.5N/A * 
preweaning lethality, incomplete penetrance2 supporting datasetsGys1em1(IMPC)BayhomozygoteEarly adultN/A * 
increased bone mineral content1 supporting datasetGys1em1(IMPC)BayheterozygoteEarly adult2.66x10-5 
decreased body length1 supporting datasetGys1em1(IMPC)BayheterozygoteEarly adult6.88x10-5 
preweaning lethality, complete penetrance1 supporting datasetGys1em1(IMPC)BayhomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gys1em1(IMPC)BayExon Deletionmouse
Gys1tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Gys1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Gys1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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