Bfsp1 | beaded filament structural protein 1, in lens-CP94

GeneMGI:101770Synonyms: filensin

Physiological systems

17 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Reproductive system Nervous system Vision/eye Behavior/neurological

13 No significant impact

7 Not tested

Gene metrics:4Significant phenotypes
2Associated diseases
Expression examined in:73Adult tissues
0Embryo tissues

Phenotypes

abnormal eye morphology2 supporting datasetsBfsp1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
small superior vagus ganglion1 supporting datasetBfsp1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
enlarged uterus1 supporting datasetBfsp1tm1b(EUCOMM)WtsihomozygoteEarly adultN/A * 
increased startle reflex1 supporting datasetBfsp1tm1b(EUCOMM)WtsihomozygoteEarly adult9.65x10-8 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Bfsp1tm1a(EUCOMM)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Bfsp1tm1b(EUCOMM)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Bfsp1tm1e(EUCOMM)WtsiTargeted, non-conditional alleleES Cell

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