Elk3 | ELK3, member of ETS oncogene family

GeneMGI:101762Synonyms: Net, D430049E23Rik, +2 more

Physiological systems

20 / 24 physiological systems tested

4 Significantly impacted by the knock-out

 Homeostasis/metabolism Nervous system Vision/eye Cardiovascular system

16 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Viability data
Body weight measurements
Embryo imaging data
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal eye morphology1 supporting datasetElk3Elk3homozygoteEarly adult2.09x10-5 
abnormal retina vasculature morphology1 supporting datasetElk3Elk3homozygoteEarly adult3.8x10-5 
increased circulating cholesterol level1 supporting datasetElk3em1(IMPC)IcsheterozygoteEarly adult5.61x10-7 
increased circulating alkaline phosphatase level1 supporting datasetElk3em1(IMPC)IcsheterozygoteEarly adult7.18x10-7 
decreased prepulse inhibition1 supporting datasetElk3Elk3homozygoteEarly adult2.05x10-7 
increased circulating HDL cholesterol level1 supporting datasetElk3em1(IMPC)IcsheterozygoteEarly adult8.3x10-5 
abnormal retina blood vessel pattern1 supporting datasetElk3Elk3homozygoteEarly adult3.8x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Elk3em1(IMPC)IcsDeletionmouse
Elk3tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
es cell

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