Syt4 | synaptotagmin IV

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased circulating serum albumin level1 supporting datasetSyt4em2(IMPC)HhomozygoteEarly adult5.72x10-6 
hyperactivity6 supporting datasetsSyt4em2(IMPC)HhomozygoteEarly adult2.43x10-11 
increased blood urea nitrogen level1 supporting datasetSyt4em2(IMPC)HhomozygoteEarly adult7.23x10-7 
decreased circulating fructosamine level1 supporting datasetSyt4em2(IMPC)HhomozygoteEarly adult7.66x10-7 
abnormal gait1 supporting datasetSyt4em2(IMPC)HhomozygoteEarly adult7.95x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Syt4em2(IMPC)HExon Deletionmouse
Syt4tm1(KOMP)VlcgReporter-tagged deletion allele (with selection cassette)ES Cell
Syt4tm301876(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector
Syt4tm93948(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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