Slc1a3 | solute carrier family 1 (glial high affinity glutamate transporter), member 3

GeneMGI:99917Synonyms: Eaat1, B430115D02Rik, +3 more

Physiological systems

17 / 24 physiological systems tested

1 Significantly impacted by the knock-out

 Behavior/neurological

16 No significant impact

7 Not tested

Gene metrics:2Significant phenotypes
3Associated diseases
Expression examined in:48Adult tissues
50Embryo tissues

Phenotypes

increased vertical activity1 supporting datasetSlc1a3tm1.1(KOMP)MbpheterozygoteEarly adult9.25x10-5 
abnormal sleep behavior1 supporting datasetSlc1a3tm1.1(KOMP)MbpheterozygoteEarly adult6.34x10-5 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Slc1a3tm1(KOMP)MbpReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
mouse
Slc1a3tm1.1(KOMP)MbpReporter-tagged deletion allele (post Cre, with no selection cassette)mouse
Slc1a3tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Slc1a3tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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