Smarca2 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2

GeneMGI:99603Synonyms: Snf2l2, brm, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Homeostasis/metabolism Behavior/neurological

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:4Significant phenotypes
4Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

hyperactivity5 supporting datasetsSmarca2em1(IMPC)JhomozygoteEarly adult1.46x10-10 
increased circulating phosphate level1 supporting datasetSmarca2em1(IMPC)JhomozygoteEarly adult6.07x10-6 
increased circulating bilirubin level1 supporting datasetSmarca2em1(IMPC)JhomozygoteEarly adult2.25x10-12 
increased circulating aspartate transaminase level1 supporting datasetSmarca2em1(IMPC)JhomozygoteEarly adult1.27x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Smarca2em1(IMPC)JExon Deletionmouse
Smarca2tm1a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Smarca2tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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