Cdh11 | cadherin 11

GeneMGI:99217Synonyms: Cad11, osteoblast-cadherin, +1 more

Physiological systems

20 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Homeostasis/metabolism Reproductive system Endocrine/exocrine gland Integument Growth/size/body region Liver/biliary system Behavior/neurological Craniofacial Renal/urinary system

11 No significant impact

4 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:23Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



hyperactivity	2 supporting datasets	Cdh11^em1(IMPC)Mbp	homozygote	Early adult	3.82x10^-9
abnormal skin morphology	1 supporting dataset	Cdh11^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased locomotor activity	1 supporting dataset	Cdh11^em1(IMPC)Mbp	homozygote	Early adult	1.6x10^-5
small liver	2 supporting datasets	Cdh11^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
enlarged kidney	1 supporting dataset	Cdh11^em1(IMPC)Mbp	homozygote	Early adult	N/A ^*
decreased thigmotaxis	2 supporting datasets	Cdh11^em1(IMPC)Mbp	homozygote	Early adult	1.86x10^-12
decreased anxiety-related response	1 supporting dataset	Cdh11^em1(IMPC)Mbp	homozygote	Early adult	1.58x10^-12
increased circulating alkaline phosphatase level	1 supporting dataset	Cdh11^em1(IMPC)Mbp	homozygote	Early adult	3.19x10^-6
decreased body length	1 supporting dataset	Cdh11^em1(IMPC)Mbp	homozygote	Early adult	3.12x10^-9
decreased grip strength	1 supporting dataset	Cdh11^em1(IMPC)Mbp	homozygote	Early adult	1.08x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Cdh11.

Associated images

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Histopathology

There is no histopathology data found for Cdh11.

IMPC related publications

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External links

No external links available for Cdh11.

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*Cdh11^em1(IMPC)Mbp*	Exon Deletion	‌	mouse
*Cdh11^{tm269911(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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