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Gene: Rxrg MGI:98216

Gene Summary

Name:

retinoid X receptor gamma

Synonyms:

Nr2b3

Order Alleles

IMPC Data Collections

No Body Weight Data
No Embryo Imaging Data
No Viability Data

IMPC Phenotype Summary

Significant

Not Significant

Not tested

View all our phenotype data below

Phenotypes

The IMPC applies a panel of phenotyping screens to characterise single-gene knockout mice by comparison to wild types. Click on the different tabs to visualise significant phenotypes identified by the IMPC, as well as all data that was measured.

Phenotype	Allele	Zyg	Life Stage	P Value
increased circulating cholesterol level	Rxrg^Rxrg	HOM	Early adult	9.28×10^-14
increased circulating HDL cholesterol level	Rxrg^Rxrg	HOM	Early adult	4.63×10^-14
decreased grip strength	Rxrg^Rxrg	HOM	Early adult	2.22×10^-06
decreased thermal nociceptive threshold	Rxrg^Rxrg	HOM	Early adult	4.22×10^-05
increased circulating triglyceride level	Rxrg^Rxrg	HOM	Early adult	3.25×10^-07
abnormal bone mineralization	Rxrg^Rxrg	HOM	Early adult	1.04×10^-06

Download data as: TSV XLS

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Viewing: all phenotypes

lacZ Expression

Expression data not available

Associated Images

Images submitted by IMPC centres for a selection of procedures. Each set of images is available to view in our image comparator.

Phenotype associated images not available

Human diseases caused by Rxrg mutations

The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.

Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.

Human diseases associated with Rxrg (0 diseases)
Human diseases predicted to be associated with Rxrg (320 diseases)

No human diseases associated to this gene by orthology or annotation.

The table below shows human diseases predicted to be associated to Rxrg by phenotypic similarity.

Disease	Matching phenotypes	Source
Thomsen And Becker Disease	Myotonia	ORPHA:614
Hypertriglyceridemia 2	Hypercholesterolemia, Hypertriglyceridemia, Decreased HDL cholesterol concentration	OMIM:619324
Cholesterol-Ester Transfer Protein Deficiency	Hypotriglyceridemia, Increased HDL cholesterol concentration, Hyperlipidemia, Hyperlipoproteinemi...	ORPHA:79506
Proximal Myotonic Myopathy	Myotonia	ORPHA:606
Atherosclerosis Susceptibility	Hypertriglyceridemia, Decreased HDL cholesterol concentration	OMIM:108725
Xanthomatosis, Susceptibility To	Hypercholesterolemia	OMIM:602247
Rippling Muscle Disease 1	Percussion-induced rapid rolling muscle contractions, Muscle mounding	OMIM:600332
Myotonia Congenita, Autosomal Dominant	Handgrip myotonia, Myotonia with warm-up phenomenon, Myotonia, Percussion myotonia, EMG: myotonic...	OMIM:160800
Thyroid Hormone Metabolism, Abnormal, 2	Hypercholesterolemia	OMIM:619855
Sitosterolemia 2	Hypercholesterolemia, Elevated circulating sitosterol concentration	OMIM:618666
Hypoalphalipoproteinemia, Primary, 1	Decreased HDL cholesterol concentration, Hypertriglyceridemia	OMIM:604091
Hyperlipoproteinemia, Type Ii, And Deafness	Increased LDL cholesterol concentration, Hypercholesterolemia, Hypertriglyceridemia	OMIM:144300
Hypercholesterolemia, Familial, 4	Decreased LDL cholesterol concentration, Hypercholesterolemia, Hypertriglyceridemia	OMIM:603813
Glycogen Storage Disease Vi	Hyperlipidemia, Hypertriglyceridemia, Hypercholesterolemia	OMIM:232700
Fish-Eye Disease	Increased VLDL cholesterol concentration, Increased LDL cholesterol concentration, Decreased HDL ...	OMIM:136120
Myopathy, Granulovacuolar Lobular, With Electrical Myotonia	Myotonia	OMIM:254950
Paramyotonia Congenita Of Von Eulenburg	Handgrip myotonia, Myotonia, Percussion myotonia, Myotonia of the face, Cold-sensitive myotonia, ...	ORPHA:684
Coronary Artery Disease, Autosomal Dominant 2	Osteoporosis, Increased LDL cholesterol concentration, Gout, Hypertriglyceridemia	OMIM:610947
Glycogen Storage Disease Due To Glycogen Debranching Enzyme Deficiency	Hypertriglyceridemia	ORPHA:366
Myotonia Congenita, Autosomal Recessive	Percussion myotonia, Myotonia with warm-up phenomenon, Myotonia, EMG: myotonic runs	OMIM:255700
Muscular Dystrophy, Barnes Type	Myotonia	OMIM:158800
Hyperlipidemia, Familial Combined, 3	Xanthelasma, Increased LDL cholesterol concentration, Hyperlipidemia, Increased VLDL cholesterol ...	OMIM:144250
Coronary Artery Disease, Autosomal Dominant, 1	Hypercholesterolemia	OMIM:608320
Proteasome-Associated Autoinflammatory Syndrome 5	Hypertriglyceridemia	OMIM:619175
Paramyotonia Congenita	Handgrip myotonia, Percussion myotonia, Paradoxical myotonia	OMIM:168300
Emery-Dreifuss Muscular Dystrophy 3, Autosomal Recessive	Elbow flexion contracture, Increased LDL cholesterol concentration, Elevated circulating creatine...	OMIM:616516
Morbid Obesity And Spermatogenic Failure	Increased LDL cholesterol concentration, Hypercholesterolemia, Hypertriglyceridemia, Decreased HD...	OMIM:615703
Hepatic Lipase Deficiency	Increased HDL cholesterol concentration, Hypertriglyceridemia, Hypercholesterolemia	OMIM:614025
Diarrhea 7, Protein-Losing Enteropathy Type	Hypoalbuminemia, Hyperlipidemia, Hypercholesterolemia	OMIM:615863
Congenital Disorder Of Glycosylation, Type Iip	Increased LDL cholesterol concentration, Hypercholesterolemia, Decreased circulating ceruloplasmi...	OMIM:616829
Hypertriglyceridemia 1	Hypertriglyceridemia, Increased VLDL cholesterol concentration	OMIM:145750
Analbuminemia	Hypoalbuminemia, Increased LDL cholesterol concentration, Elevated circulating transferrin concen...	OMIM:616000
Hypothyroidism, Congenital, Nongoitrous, 8	Hypercholesterolemia	OMIM:301033
Hyperkalemic Periodic Paralysis	Myotonia	OMIM:170500
Rippling Muscle Disease 2	Percussion-induced rapid rolling muscle contractions, Muscle mounding	OMIM:606072
Hypophosphatemic Rickets, Autosomal Recessive, 1	Rickets, Hypophosphatemic rickets, Hypophosphatemia, Craniosynostosis, Increased bone mineral den...	OMIM:241520
Brody Disease	Percussion myotonia, Myotonia	OMIM:601003
Lipase Deficiency, Combined	Hypertriglyceridemia	OMIM:246650
Cholestasis, Progressive Familial Intrahepatic, 10	Hypoalbuminemia, Increased total bilirubin, Increased serum bile acid concentration, Hypercholest...	OMIM:619868
Glycogen Storage Disease Ixa1	Hypercholesterolemia, Hyperuricemia, Hypertriglyceridemia	OMIM:306000
Myotonia, Potassium-Aggravated	Handgrip myotonia, Myotonia, Percussion myotonia	OMIM:608390
Lecithin:Cholesterol Acyltransferase Deficiency	Hypertriglyceridemia, Decreased HDL cholesterol concentration	OMIM:245900
Hypokalemic Periodic Paralysis, Type 2	Myotonia	OMIM:613345
Hemophagocytic Lymphohistiocytosis, Familial, 3	Hypertriglyceridemia	OMIM:608898
Hypercholesterolemia, Familial, 3	Xanthelasma, Hypercholesterolemia, Abnormal LDL cholesterol concentration	OMIM:603776
Glycogen Storage Disease Due To Muscle Phosphofructokinase Deficiency	Myotonia	ORPHA:371
Distal Myopathy, Tateyama Type	Abnormal circulating creatine kinase concentration, Hypercholesterolemia	ORPHA:488650
Microcephalic Primordial Dwarfism-Insulin Resistance Syndrome	Hypertriglyceridemia	ORPHA:436182
Cholesteryl Ester Storage Disease	Hypercholesterolemia, Hypertriglyceridemia	ORPHA:75234
Hyperlipidemia Due To Hepatic Triacylglycerol Lipase Deficiency	Increased HDL cholesterol concentration, Hypertriglyceridemia	ORPHA:140905
Encephalopathy, Progressive, With Or Without Lipodystrophy	Hypertriglyceridemia	OMIM:615924
Hypertriglyceridemia, Transient Infantile	Hypertriglyceridemia	OMIM:614480
Hypercholesterolemia, Familial, 2	Xanthelasma, Increased LDL cholesterol concentration, Hypercholesterolemia	OMIM:144010
Niemann-Pick Disease, Type B	Increased LDL cholesterol concentration, Decreased HDL cholesterol concentration, Hypertriglyceri...	OMIM:607616
Hyperinsulinemic Hypoglycemia, Familial, 8	Increased C-peptide level, Hypercholesterolemia, Hyperammonemia	OMIM:620211
Spinocerebellar Ataxia With Axonal Neuropathy Type 1	Hypoalbuminemia, Hypercholesterolemia	ORPHA:94124
Lipodystrophy, Congenital Generalized, Type 3	Hypercholesterolemia, Hypocalcemia, Hypertriglyceridemia	OMIM:612526
Spinocerebellar Ataxia, Autosomal Recessive, With Axonal Neuropathy 1	Hypoalbuminemia, Hypercholesterolemia	OMIM:607250
Apolipoprotein C-Ii Deficiency	Hypercholesterolemia, Decreased circulating apolipoprotein C-II concentration, Increased circulat...	OMIM:207750
Myotonia Fluctuans	Handgrip myotonia, Myotonia with warm-up phenomenon, Myotonia of the lower limb, Myotonia of the ...	ORPHA:99734
Obesity Due To Melanocortin 4 Receptor Deficiency	Hypertriglyceridemia	ORPHA:71529
Hypophosphatemic Bone Disease	Hypophosphatemia, Rickets, Osteomalacia	OMIM:146350
Hypercholanemia, Familial 1	Steatorrhea, Rickets, Increased serum bile acid concentration	OMIM:607748
Hypokalemic Periodic Paralysis, Type 1	Myotonia	OMIM:170400
Congenital Disorder Of Glycosylation, Type Iio	Increased LDL cholesterol concentration, Hypercholesterolemia, Elevated circulating creatine kina...	OMIM:616828
Morgagni-Stewart-Morel Syndrome	Hyperuricemia, Hypercholesterolemia, Osteoarthritis, Osteoporosis, Hyperostosis frontalis interna	ORPHA:77296
Body Mass Index Quantitative Trait Locus 19	Hyperlipidemia, Hypertriglyceridemia	OMIM:617885
Hypobetalipoproteinemia, Familial, 1	Decreased HDL cholesterol concentration, Hypocholesterolemia, Decreased LDL cholesterol concentra...	OMIM:615558
Citrullinemia, Type Ii, Neonatal-Onset	Hypermethioninemia, Decreased HDL cholesterol concentration, Hyperbilirubinemia, Hyperthreoninemi...	OMIM:605814
Temple Syndrome Due To Paternal 14Q32.2 Hypomethylation	Hypercholesterolemia, Joint hypermobility	ORPHA:254531
Renal Tubular Acidosis, Proximal	Elevated circulating creatinine concentration, Rickets, Osteomalacia	OMIM:179830
Hypophosphatemic Rickets, Autosomal Dominant	Hypophosphatemia, Hypophosphatemic rickets, Rickets, Osteomalacia	OMIM:193100
Hemophagocytic Lymphohistiocytosis, Familial, 4	Increased circulating ferritin concentration, Hypertriglyceridemia	OMIM:603552
Abdominal Obesity-Metabolic Syndrome 4	Elevated hemoglobin A1c, Increased LDL cholesterol concentration, Hypertriglyceridemia, Decreased...	OMIM:618620
Nephrotic Syndrome, Type 2	Hypoalbuminemia, Hyperlipidemia	OMIM:600995
Protoporphyria, Erythropoietic, 1	Hypertriglyceridemia	OMIM:177000
Temple Syndrome	Joint hypermobility, Flexion contracture, Hypercholesterolemia, Hypertriglyceridemia	OMIM:616222
Bile Acid Conjugation Defect 1	Conjugated hyperbilirubinemia, Rickets	OMIM:619232
Lipodystrophy, Familial Partial, Type 4	Hypertriglyceridemia	OMIM:613877
Immunodeficiency 109 With Lymphoproliferation	Hypertriglyceridemia	OMIM:620282
Axial Osteomalacia	Increased bone mineral density, Osteomalacia, Elevated circulating creatine kinase concentration	OMIM:109130
Plin1-Related Familial Partial Lipodystrophy	Hypertriglyceridemia	ORPHA:280356
Lymphoproliferative Syndrome, X-Linked, 2	Increased circulating ferritin concentration, Hypertriglyceridemia	OMIM:300635
Hemophagocytic Lymphohistiocytosis, Familial, 5, With Or Without Microvillus Inclusion Disease	Hypertriglyceridemia, Increased circulating ferritin concentration	OMIM:613101
Myotonia With Skeletal Abnormalities And Impaired Intellectual Development	Myotonia	OMIM:255710
Rajab Interstitial Lung Disease With Brain Calcifications 2	Hypoalbuminemia, Joint hypermobility, Hypertriglyceridemia	OMIM:619013
Dnajb6-Related Limb-Girdle Muscular Dystrophy D1	Percussion myotonia	ORPHA:34516
Laron Syndrome	Hypercholesterolemia, Osteoarthritis	ORPHA:633
Acetazolamide-Responsive Myotonia	Myotonia	ORPHA:99736
Lipodystrophy, Familial Partial, Type 1	Hypertriglyceridemia	OMIM:608600
Abdominal Obesity-Metabolic Syndrome 3	Increased LDL cholesterol concentration, Hypercholesterolemia, Hypertriglyceridemia	OMIM:615812
Hyperlipoproteinemia, Type I	Lactescent serum, Hyperlipidemia, Increased circulating chylomicron concentration, Hypercholester...	OMIM:238600
Glycosylphosphatidylinositol Biosynthesis Defect 17	Osteomyelitis, Hypertriglyceridemia	OMIM:618010
Ataxia-Oculomotor Apraxia 4	Hypoalbuminemia, Hypercholesterolemia, Elevated circulating alpha-fetoprotein concentration	OMIM:616267
Renal Tubular Acidosis, Distal, 1	Osteomalacia, Pathologic fracture, Elevated circulating creatinine concentration, Hypocalcemia, H...	OMIM:179800
Citrullinemia, Type Ii, Adult-Onset	Elevated plasma citrulline, Hyperammonemia, Hyperargininemia, Hypertriglyceridemia	OMIM:603471
Lcat Deficiency	Hypertriglyceridemia, Decreased circulating apolipoprotein A-I concentration, Decreased HDL chole...	ORPHA:650
Idiopathic Steroid-Resistant Nephrotic Syndrome	Hypoalbuminemia, Hypercholesterolemia, Abnormal circulating lipid concentration, Hypertriglycerid...	ORPHA:567548
Renal Tubular Acidosis Iii	Hypokalemia, Rickets, Osteomalacia	OMIM:267200
Ataxia With Vitamin E Deficiency	Xanthelasma, Increased LDL cholesterol concentration, Hypercholesterolemia, Hypertriglyceridemia	OMIM:277460
Dysbetalipoproteinemia	Xanthelasma, Increased LDL cholesterol concentration, Gout, Hypertriglyceridemia, Hypercholestero...	ORPHA:412
Neonatal Intrahepatic Cholestasis Due To Citrin Deficiency	Hypoalbuminemia, Elevated circulating alpha-fetoprotein concentration, Hypermethioninemia, Abnorm...	ORPHA:247598
Lipodystrophy, Familial Partial, Type 5	Increased C-peptide level, Hypertriglyceridemia	OMIM:615238
Hypercholesterolemia Due To Cholesterol 7Alpha-Hydroxylase Deficiency	Increased LDL cholesterol concentration, Hypercholesterolemia, Hypertriglyceridemia	ORPHA:209902
Tangier Disease	Elevated circulating apolipoprotein A-II concentration, Decreased HDL cholesterol concentration, ...	OMIM:205400
Mandibular Hypoplasia, Deafness, Progeroid Features, And Lipodystrophy Syndrome	Osteoporosis, Joint contracture, Hypertriglyceridemia	OMIM:615381
Mandibuloacral Dysplasia	Increased circulating free fatty acid level, Contractures of the large joints, Acroosteolysis of ...	ORPHA:2457
Congenital Generalized Lipodystrophy	Hypercholesterolemia, Increased C-peptide level, Bone cyst, Hypertriglyceridemia	ORPHA:528
Ataxia, Early-Onset, With Oculomotor Apraxia And Hypoalbuminemia	Hypoalbuminemia, Hypercholesterolemia, Elevated circulating creatine kinase concentration	OMIM:208920
Immunodeficiency 114, Folate-Responsive	Increased circulating ferritin concentration, Hypertriglyceridemia	OMIM:620603
Vitamin D-Dependent Rickets, Type 2B, With Normal Vitamin D Receptor	Delayed epiphyseal ossification, Rickets, Rickets of the lower limbs, Sparse bone trabeculae, Gen...	OMIM:600785
Hyperlipoproteinemia, Type Id	Increased circulating chylomicron concentration, Decreased HDL cholesterol concentration, Hyperli...	OMIM:615947
Smith-Magenis Syndrome	Hypercholesterolemia, Hypertriglyceridemia	OMIM:182290
Congenital Analbuminemia	Hypoalbuminemia, Hyperlipidemia, Hypercholesterolemia, Hypoproteinemia, Increased alpha-globulin	ORPHA:86816
Citrullinemia Type Ii	Hypoalbuminemia, Decreased HDL cholesterol concentration, Hyperlipidemia, Acute hyperammonemia, H...	ORPHA:247585
Hypophosphatasia, Adult	Rickets, Osteomalacia, Pathologic fracture, Increased susceptibility to fractures, Recurrent frac...	OMIM:146300
Galactokinase Deficiency	Hypercholesterolemia, Hypergalactosemia, Increased level of galactitol in plasma	ORPHA:79237
Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	Elbow flexion contracture, Joint stiffness, Increased LDL cholesterol concentration, Decreased ce...	ORPHA:98855
Lipodystrophy, Familial Partial, Type 3	Decreased HDL cholesterol concentration, Hyperuricemia, Hypertriglyceridemia	OMIM:604367
Bile Acid Synthesis Defect, Congenital, 1	Steatorrhea, Hypocholesterolemia, Conjugated hyperbilirubinemia, Rickets	OMIM:607765
Myopathy, X-Linked, With Excessive Autophagy	Myotonia	OMIM:310440
Glycogen Storage Disease Due To Glucose-6-Phosphatase Deficiency	Hyperlipidemia, Hyperuricemia	ORPHA:364
Cog4-Cdg	Hypercholesterolemia	ORPHA:263501
Hemophagocytic Lymphohistiocytosis, Familial, 1	Hypoalbuminemia, Increased circulating ferritin concentration, Increased total bilirubin, Decreas...	OMIM:267700
Severe Neurodegenerative Syndrome With Lipodystrophy	Hypertriglyceridemia	ORPHA:363400
Temple Syndrome Due To Maternal Uniparental Disomy Of Chromosome 14	Hypercholesterolemia, Joint hypermobility	ORPHA:96184
Xp21 Deletion Syndrome	Joint hypermobility, Elevated circulating creatine kinase concentration, Hypertriglyceridemia, Os...	ORPHA:261476
Werner Syndrome	Osteoporosis, Elevated hemoglobin A1c, Reduced bone mineral density, Hypertriglyceridemia	OMIM:277700
T-Cell Lymphoma, Subcutaneous Panniculitis-Like	Hypertriglyceridemia, Increased circulating ferritin concentration	OMIM:618398
Autosomal Dominant Adult-Onset Proximal Spinal Muscular Atrophy	Myotonia	ORPHA:209335
X-Linked Emery-Dreifuss Muscular Dystrophy	Elbow flexion contracture, Joint stiffness, Increased LDL cholesterol concentration, Decreased ce...	ORPHA:98863
Spinocerebellar Ataxia With Axonal Neuropathy Type 2	Hypoalbuminemia, Elevated circulating creatine kinase concentration, Hypercholesterolemia, Elevat...	ORPHA:64753
Autosomal Dominant Emery-Dreifuss Muscular Dystrophy	Elbow flexion contracture, Joint stiffness, Increased LDL cholesterol concentration, Decreased ce...	ORPHA:98853
Emery-Dreifuss Muscular Dystrophy	Elbow flexion contracture, Joint stiffness, Increased LDL cholesterol concentration, Decreased ce...	ORPHA:261
Nephrotic Syndrome, Type 11	Hypoalbuminemia, Hypercholesterolemia	OMIM:616730
Episodic Ataxia, Type 2	Myotonia	OMIM:108500
Pancreatic Lipase Deficiency	Steatorrhea, Hypocholesterolemia	OMIM:614338
Glycogen Storage Disease Due To Liver Glycogen Phosphorylase Deficiency	Osteoporosis, Osteopenia, Hyperlipidemia	ORPHA:369
Cholesteryl Ester Storage Disease	Increased LDL cholesterol concentration, Hypertriglyceridemia, Hypercholesterolemia, Decreased HD...	OMIM:278000
Autosomal Dominant Hypophosphatemic Rickets	Hypophosphatemia, Rickets, Hypocalcemia, Osteomalacia	ORPHA:89937
Sitosterolemia 1	Hyperapobetalipoproteinemia, Xanthelasma, Reduced haptoglobin level, Elevated circulating sitoste...	OMIM:210250
Acquired Hemophagocytic Lymphohistiocytosis Associated With Malignant Disease	Elevated circulating C-reactive protein concentration, Hyperbilirubinemia, Increased circulating ...	ORPHA:158057
Akt2-Related Familial Partial Lipodystrophy	Hypertriglyceridemia	ORPHA:79085
Autosomal Recessive Axonal Neuropathy With Neuromyotonia	Handgrip myotonia, Myotonia, Percussion-induced rapid rolling muscle contractions	ORPHA:324442
Hereditary Hypophosphatemic Rickets With Hypercalciuria	Increased circulating beta-C-terminal telopeptide concentration, Osteomalacia, Pathologic fractur...	ORPHA:157215
Fanconi-Bickel Syndrome	Osteopenia, Hypophosphatemia, Rickets, Hypertriglyceridemia	ORPHA:2088
Cholestasis, Progressive Familial Intrahepatic, 8	Hypercholesterolemia, Elevated circulating alpha-fetoprotein concentration, Conjugated hyperbilir...	OMIM:619662
Mandibuloacral Dysplasia With Type A Lipodystrophy	Osteopenia, Elbow flexion contracture, Joint stiffness, Hyperlipidemia, Acroosteolysis of distal ...	OMIM:248370
Cholestasis-Lymphedema Syndrome	Hyperlipidemia, Conjugated hyperbilirubinemia	OMIM:214900
Fanconi Renotubular Syndrome 2	Osteopenia, Rickets, Osteomalacia, Hypophosphatemia, Recurrent fractures	OMIM:613388
Hypocalcemic Vitamin D-Resistant Rickets	Coarse metaphyseal trabecularization, Osteomalacia, Recurrent fractures, Hypocalcemia, Hypophosph...	ORPHA:93160
Hypophosphatemic Rickets, X-Linked Recessive	Delayed epiphyseal ossification, Rickets, Osteomalacia, Hypophosphatemic rickets, Sparse bone tra...	OMIM:300554
Myofibrillar Myopathy 10	Percussion myotonia	OMIM:619040
Myotonia Permanens	Myotonia	ORPHA:99735
Vitamin D Hydroxylation-Deficient Rickets, Type 1B	Delayed epiphyseal ossification, Rickets, Hypocalcemia, Sparse bone trabeculae, Hypophosphatemia,...	OMIM:600081
Renal Tubular Acidosis, Distal, 3, With Or Without Sensorineural Hearing Loss	Hypokalemia, Rickets	OMIM:602722
Smith-Magenis Syndrome	Joint stiffness, Hypercholesterolemia, Hypertriglyceridemia	ORPHA:819
Focal Segmental Glomerulosclerosis 1	Hypoalbuminemia, Hyperlipidemia	OMIM:603278
Fanconi Renotubular Syndrome 3	Elevated circulating creatinine concentration, Rickets	OMIM:615605
Macrophage Activation Syndrome	Hypoalbuminemia, Increased circulating ferritin concentration, Hypertriglyceridemia, Elevated cir...	ORPHA:158061
Cholestasis, Progressive Familial Intrahepatic, 1	Osteopenia, Conjugated hyperbilirubinemia, Rickets	OMIM:211600
Palmoplantar Hyperkeratosis With Squamous Cell Carcinoma Of Skin And 46,Xx Sex Reversal	Hypercholesterolemia, Hypertriglyceridemia	OMIM:610644
9Q31.1Q31.3 Microdeletion Syndrome	Hypercholesterolemia	ORPHA:401923
Richieri Costa-Da Silva Syndrome	Handgrip myotonia, Myotonia of the upper limb	ORPHA:3101
Megalocornea-Intellectual Disability Syndrome	Osteopenia, Hypercholesterolemia, Joint hypermobility	ORPHA:2479
Neuropathy, Hereditary Motor And Sensory, Okinawa Type	Hyperlipidemia, Mildly elevated creatine kinase	OMIM:604484
Glycogen Storage Disease Ixc	Hypertriglyceridemia	OMIM:613027
Episodic Ataxia Type 1	Myotonia	ORPHA:37612
Hypophosphatemic Rickets With Hypercalciuria, Hereditary	Delayed epiphyseal ossification, Rickets, Hypophosphatemic rickets, Sparse bone trabeculae, Hypop...	OMIM:241530
Glycogen Storage Disease Iii	Hyperlipidemia, Elevated circulating creatine kinase concentration	OMIM:232400
Glycogen Storage Disease Due To Liver And Muscle Phosphorylase Kinase Deficiency	Osteoporosis, Elevated circulating creatine kinase concentration, Hypercholesterolemia, Hypertrig...	ORPHA:79240
Griscelli Syndrome Type 1	Hyperlipidemia	ORPHA:79476
Cidec-Related Familial Partial Lipodystrophy	Hypertriglyceridemia	ORPHA:435651
Zebra Body Myopathy	Handgrip myotonia	ORPHA:97240
Immunodeficiency 80 With Or Without Congenital Cardiomyopathy	Increased circulating ferritin concentration, Hypertriglyceridemia	OMIM:619313
Lipe-Related Familial Partial Lipodystrophy	Hypertriglyceridemia, Elevated circulating creatine kinase concentration	ORPHA:435660
Lipodystrophy, Congenital Generalized, Type 4	Osteopenia, Elevated circulating creatine kinase concentration, Hypertriglyceridemia, Osteoporosi...	OMIM:613327
Reni Syndrome	Hypoalbuminemia, Hypertriglyceridemia	OMIM:617575
Glycogen Storage Disease Due To Liver Phosphorylase Kinase Deficiency	Osteoporosis, Elevated circulating creatine kinase concentration, Hypercholesterolemia, Hypertrig...	ORPHA:264580
Congenital Disorder Of Glycosylation, Type Iiaa	Hypercholesterolemia, Hyperammonemia, Knee flexion contracture	OMIM:620454
Lipodystrophy, Familial Partial, Type 6	Hyperlipidemia, Abnormal circulating lipid concentration, Elevated circulating creatine kinase co...	OMIM:615980
Galloway-Mowat Syndrome 7	Hypercholesterolemia	OMIM:618348
Fanconi Renotubular Syndrome 1	Hypokalemia, Hypophosphatemia, Rickets, Osteomalacia	OMIM:134600
Obesity Due To Congenital Leptin Deficiency	Hypertriglyceridemia	ORPHA:66628
Neuhauser Syndrome	Osteopenia, Hypercholesterolemia	OMIM:249310
Myotonic Dystrophy 1	Myotonia	OMIM:160900
Lysinuric Protein Intolerance	Osteopenia, Increased circulating ferritin concentration, Decreased HDL cholesterol concentration...	ORPHA:470
Severe Intellectual Disability-Short Stature-Behavioral Abnormalities-Facial Dysmorphism Syndrome	Myotonia	ORPHA:391307
Obesity Due To Leptin Receptor Gene Deficiency	Hypertriglyceridemia	ORPHA:179494
Pparg-Related Familial Partial Lipodystrophy	Hyperuricemia, Hypertriglyceridemia	ORPHA:79083
Infantile Systemic Hyalinosis	Osteopenia, Osteomalacia, Camptodactyly of finger, Joint stiffness, Increased susceptibility to f...	ORPHA:2176
Vitamin D Hydroxylation-Deficient Rickets, Type 1A	Delayed epiphyseal ossification, Rickets, Hypocalcemia, Sparse bone trabeculae, Hypophosphatemia,...	OMIM:264700
Familial Partial Lipodystrophy, Dunnigan Type	Hypertriglyceridemia	ORPHA:2348
Acquired Generalized Lipodystrophy	Unicameral bone cyst, Abnormal circulating lipid concentration, Hypertriglyceridemia	ORPHA:79086
Hemophagocytic Lymphohistiocytosis, Familial, 2	Hypoalbuminemia, Increased total bilirubin, Increased circulating ferritin concentration, Hyponat...	OMIM:603553
Renal Tubular Acidosis, Distal, 4, With Hemolytic Anemia	Hypokalemia, Rickets	OMIM:611590
Proteasome-Associated Autoinflammatory Syndrome 3	Flexion contracture, Arthritis, Hypertriglyceridemia	OMIM:617591
Cholestasis-Lymphedema Syndrome	Reduced bone mineral density, Hyperlipidemia	ORPHA:1414
Congenital Bile Acid Synthesis Defect Type 2	Rickets, Hyperbilirubinemia, Abnormal serum bile acid concentration, Steatorrhea, Conjugated hype...	ORPHA:79303
Dent Disease 1	Delayed epiphyseal ossification, Rickets, Osteomalacia, Sparse bone trabeculae, Hypophosphatemia,...	OMIM:300009
Vitamin D-Dependent Rickets, Type 2A	Delayed epiphyseal ossification, Rickets, Sparse bone trabeculae, Hypophosphatemia, Thin bony cor...	OMIM:277440
Hypophosphatemic Rickets And Hyperparathyroidism	Hypophosphatemia, Hypophosphatemic rickets, Hypercalcemia, Rickets	OMIM:612089
Microtriplication 11Q24.1	Limitation of joint mobility, Hyperlipidemia	ORPHA:289522
Gaisböck Syndrome	Gout, Hyperuricemia, Hypercholesterolemia, Hypertriglyceridemia, Hyperproteinemia, Increased circ...	ORPHA:90041
Myotonic Dystrophy 2	Handgrip myotonia, Myotonia	OMIM:602668
Hypophosphatemic Rickets, X-Linked Dominant	Rickets, Osteomalacia, Hypophosphatemic rickets, Hypophosphatemia, Osteoarthritis, Abnormal circu...	OMIM:307800
Familial Hemophagocytic Lymphohistiocytosis	Hypoalbuminemia, Increased circulating ferritin concentration, Hypertriglyceridemia	ORPHA:540
Acquired Aneurysmal Subarachnoid Hemorrhage	Hypercholesterolemia	ORPHA:90065
Immunodeficiency 97 With Autoinflammation	Increased circulating ferritin concentration, Hypertriglyceridemia	OMIM:619802
Familial Chylomicronemia Syndrome	Hyperlipidemia, Increased circulating chylomicron concentration, Hypertriglyceridemia	ORPHA:444490
Glycogen Storage Disease Due To Glucose-6-Phosphatase Deficiency Type Ib	Osteopenia, Xanthelasma, Hyperlipidemia, Increased susceptibility to fractures, Hyperuricemia, Go...	ORPHA:79259
Isolated Thyroid-Stimulating Hormone Deficiency	Abnormal circulating thyroglobulin concentration, Neonatal hyperbilirubinemia, Hypercholesterolem...	ORPHA:90674
Primary Biliary Cholangitis	Hypoalbuminemia, Abnormal circulating lipid concentration, Xanthelasma, Hypercholesterolemia, Ste...	ORPHA:186
Prader-Willi Syndrome	Osteopenia, Decreased HDL cholesterol concentration, Hypercholesterolemia, Hypertriglyceridemia, ...	OMIM:176270
Congenital-Onset Steinert Myotonic Dystrophy	Myotonia	ORPHA:589821
Spastic Paraplegia 79B, Autosomal Recessive	Myotonia	OMIM:615491
Fanconi Renotubular Syndrome 4 With Maturity-Onset Diabetes Of The Young	Hypouricemia, Hypophosphatemia, Rickets	OMIM:616026
Fibrous Dysplasia Of Bone	Rickets, Increased circulating cortisol level, Osteomalacia, Cortical irregularity, Pathologic fr...	ORPHA:249
Hypocalcemic Vitamin D-Dependent Rickets	Delayed epiphyseal ossification, Rickets, Osteomalacia, Hypocalcemia, Increased susceptibility to...	ORPHA:289157
Low Phospholipid-Associated Cholelithiasis	Hypercholesterolemia	ORPHA:69663
Fanconi-Bickel Syndrome	Hypouricemia, Rickets, Osteomalacia, Hyperbilirubinemia, Increased serum bile acid concentration,...	OMIM:227810
Lipodystrophy, Familial Partial, Type 2	Hypercholesterolemia, Decreased HDL cholesterol concentration, Hypertriglyceridemia	OMIM:151660
H Syndrome	Camptodactyly, Osteolysis, Recurrent fractures, Hypertriglyceridemia	ORPHA:168569
Diarrhea 10, Protein-Losing Enteropathy Type	Hypoalbuminemia, Hypomagnesemia, Hypocalcemia, Hyponatremia, Hypertriglyceridemia	OMIM:618183
Hyperkalemic Periodic Paralysis	Myotonia	ORPHA:682
Autosomal Semi-Dominant Severe Lipodystrophic Laminopathy	Acroosteolysis of distal phalanges (feet), Osteolytic defects of the phalanges of the hand, Decre...	ORPHA:280365
Glycogen Storage Disease Due To Hepatic Glycogen Synthase Deficiency	Hyperlipidemia	ORPHA:2089
Neutral Lipid Storage Disease With Ichthyosis	Abnormal circulating creatine kinase concentration, Hypertriglyceridemia	ORPHA:98907
Autosomal Recessive Hypophosphatemic Rickets	Renal hypophosphatemia, Abnormal trabecular bone morphology, Pseudo-fractures, Osteomalacia, Rick...	ORPHA:289176
Gamma-Sarcoglycan-Related Limb-Girdle Muscular Dystrophy R5	EMG: myotonic runs	ORPHA:353
Dermatosparaxis Ehlers-Danlos Syndrome	Osteopenia, Rickets, Osteomalacia, Joint stiffness, Joint hypermobility, Osteoporosis	ORPHA:1901
Cystinosis	Hypokalemia, Hypophosphatemia, Rickets	ORPHA:213
Intellectual Disability-Seizures-Hypophosphatasia-Ophthalmic-Skeletal Anomalies Syndrome	Osteopenia, Joint hypermobility, Hypertriglyceridemia, Craniosynostosis, Hypercalcemia	ORPHA:369837
Nephrotic Syndrome, Type 1	Hypoalbuminemia, Hyperlipidemia, Hypoproteinemia	OMIM:256300
Lowe Oculocerebrorenal Syndrome	Elevated amniotic fluid alpha-fetoprotein, Joint contracture of the hand, Rickets, Osteomalacia, ...	OMIM:309000
Combined Deficiency Of Factor V And Factor Viii	Joint hemorrhage, Hyperlipidemia, Hyperuricemia	ORPHA:35909
Lmna-Related Cardiocutaneous Progeria Syndrome	Hypercholesterolemia, Hypertriglyceridemia	ORPHA:363618
Glycerol Kinase Deficiency	Pathologic fracture, Hyperglycerolemia, Osteoporosis, Hypertriglyceridemia	OMIM:307030
Chronic Visceral Acid Sphingomyelinase Deficiency	Osteopenia, Abnormal circulating lipid concentration, Pathologic fracture, Increased LDL choleste...	ORPHA:77293
Mccune-Albright Syndrome	Aneurysmal bone cyst, Increased circulating cortisol level, Osteomalacia, Monostotic fibrous dysp...	ORPHA:562
Lysosomal Acid Lipase Deficiency	Xanthelasma, Hyponatremia, Hypercholesterolemia, Hypertriglyceridemia, Steatorrhea, Hyperkalemia	ORPHA:275761
Classical-Like Ehlers-Danlos Syndrome Type 2	Joint hypermobility, Osteopenia, Hypertriglyceridemia	ORPHA:536532
Schwartz-Jampel Syndrome, Type 1	Percussion myotonia	OMIM:255800
Seckel Syndrome 10	Elevated hemoglobin A1c, Hypertriglyceridemia	OMIM:617253
Renal Tubulopathy, Diabetes Mellitus, And Cerebellar Ataxia	Osteoporosis, Rickets	OMIM:560000
Dent Disease	Renal hypophosphatemia, Delayed epiphyseal ossification, Rickets, Osteomalacia, Sparse bone trabe...	ORPHA:1652
Pancreatic Triacylglycerol Lipase Deficiency	Steatorrhea, Osteoporosis, Rickets, Osteomalacia	ORPHA:309031
Immunodeficiency 47	Decreased circulating copper concentration, Hypercholesterolemia, Joint hypermobility	OMIM:300972
Tangier Disease	Hypocholesterolemia, Hypertriglyceridemia	ORPHA:31150
Griscelli Syndrome Type 2	Hyperlipidemia	ORPHA:79477
Alstrom Syndrome	Hypertriglyceridemia, Hyperuricemia, Decreased HDL cholesterol concentration, Elevated hemoglobin...	OMIM:203800
Methanol Poisoning	Hyperlipidemia	ORPHA:31825
Bardet-Biedl Syndrome 20	Hypercholesterolemia	OMIM:619471
Mandibuloacral Dysplasia With Type A Lipodystrophy	Limitation of joint mobility, Hyperlipidemia, Acroosteolysis of distal phalanges (feet), Osteolyt...	ORPHA:90153
Mitochondrial Complex Iv Deficiency, Nuclear Type 23	Percussion myotonia	OMIM:620275
Neutral Lipid Storage Disease With Myopathy	Elevated circulating creatine kinase concentration, Hypertriglyceridemia	OMIM:610717
Hypocalciuric Hypercalcemia, Familial, Type Iii	Hypermagnesemia, Hypophosphatemia, Hypercalcemia, Osteomalacia	OMIM:600740
Celiac Disease, Susceptibility To, 1	Steatorrhea, Osteoporosis, Rickets, Hypocalcemia	OMIM:212750
Hemophagocytic Syndrome Associated With An Infection	Hyperproteinemia, Increased circulating ferritin concentration, Hypertriglyceridemia	ORPHA:158048
Oculocerebrorenal Syndrome Of Lowe	Osteomalacia, Hyperaldosteronism, Joint stiffness, Joint hypermobility, Hyponatremia, Hypokalemia...	ORPHA:534
X-Linked Hypophosphatemia	Limitation of joint mobility, Rickets, Hypophosphatemia, Generalized osteosclerosis, Arthritis, E...	ORPHA:89936
Mandibuloacral Dysplasia With Type B Lipodystrophy	Hyperlipidemia, Acroosteolysis of distal phalanges (feet), Calcinosis, Osteolytic defects of the ...	ORPHA:90154
Mandibuloacral Dysplasia Progeroid Syndrome	Osteopenia, Joint stiffness, Osteolytic defects of the phalanges of the hand, Hypertriglyceridemi...	OMIM:619127
Mandibuloacral Dysplasia With Type B Lipodystrophy	Hyperlipidemia, Acroosteolysis of distal phalanges (feet), Osteolytic defects of the distal phala...	OMIM:608612
Neurologic, Endocrine, And Pancreatic Disease, Multisystem, Infantile-Onset 2	Joint hypermobility, Hypertriglyceridemia	OMIM:619418
19P13.12 Microdeletion Syndrome	Craniosynostosis, Arthrogryposis multiplex congenita, Hyperlipidemia	ORPHA:254346
Glycogen Storage Disease Ia	Xanthelasma, Gout, Hyperlipidemia, Hyperuricemia, Osteoporosis	OMIM:232200
Cushing Syndrome Due To Bilateral Macronodular Adrenocortical Disease	Increased circulating cortisol level, Hyperaldosteronism, Hyperlipidemia, Increased susceptibilit...	ORPHA:189427
Chédiak-Higashi Syndrome	Hyponatremia, Hypoproteinemia, Increased circulating ferritin concentration, Hypertriglyceridemia	ORPHA:167
Idiopathic Camptocormia	Myotonia	ORPHA:1320
Stuve-Wiedemann Syndrome 1	Myotonia	OMIM:601559
Rod-Cone Dystrophy, Sensorineural Deafness, And Fanconi-Type Renal Dysfunction	Rickets, Recurrent fractures	OMIM:268315
Pura-Related Severe Neonatal Hypotonia-Seizures-Encephalopathy Syndrome Due To A Point Mutation	Handgrip myotonia	ORPHA:438216
Neu-Laxova Syndrome	Osteopenia, Rickets, Osteomalacia, Osteoporosis, Flexion contracture, Arthrogryposis multiplex co...	ORPHA:2671
Lipodystrophy, Congenital Generalized, Type 2	Elevated hemoglobin A1c, Cystic angiomatosis of bone, Hypertriglyceridemia	OMIM:269700
Lipodystrophy, Congenital Generalized, Type 1	Cystic angiomatosis of bone, Hypertriglyceridemia	OMIM:608594
Atypical Werner Syndrome	Limitation of joint mobility, Sclerosis of hand bone, Osteolytic defects of the phalanges of the ...	ORPHA:79474
Primary Fanconi Renotubular Syndrome	Hypouricemia, Decreased circulating carnitine concentration, Osteomalacia, Hypophosphatemic ricke...	ORPHA:3337
Neutral Lipid Storage Myopathy	Abnormal circulating creatine kinase concentration, Hypertriglyceridemia	ORPHA:98908
Cystinosis, Late-Onset Juvenile Or Adolescent Nephropathic Type	Rickets	OMIM:219900
Aromatase Deficiency	Delayed epiphyseal ossification, Osteopenia, Hyperlipidemia, Osteoporosis	ORPHA:91
Proteasome-Associated Autoinflammatory Syndrome 1	Camptodactyly of finger, Elbow flexion contracture, Hypertriglyceridemia, Flexion contracture of ...	OMIM:256040
Hemolytic Uremic Syndrome, Atypical, Susceptibility To, 1	Elevated circulating creatinine concentration, Hyperlipidemia, Increased blood urea nitrogen	OMIM:235400
Alagille Syndrome 1	Hypercholesterolemia, Hypertriglyceridemia	OMIM:118450
Glycogen Storage Disease Ib	Xanthelasma, Gout, Hyperlipidemia, Hyperuricemia, Osteoporosis	OMIM:232220
Immunodeficiency 87 And Autoimmunity	Elevated circulating C-reactive protein concentration, Hypokalemia, Hypertriglyceridemia	OMIM:619573
Distal Renal Tubular Acidosis	Rickets, Osteomalacia, Increased susceptibility to fractures, Hypokalemia, Reduced bone mineral d...	ORPHA:18
Carnitine Palmitoyltransferase Ii Deficiency	Elevated circulating acylcarnitine concentration, Decreased plasma free carnitine, Hyperlipidemia...	ORPHA:157
Familial Hypocalciuric Hypercalcemia	Renal hypophosphatemia, Hypermagnesemia, Osteomalacia, Hypocalcemic seizures, Hypercalcemia	ORPHA:405
Schwartz-Jampel Syndrome	Myotonia	ORPHA:800
Rajab Interstitial Lung Disease With Brain Calcifications 1	Hypoalbuminemia, Osteopenia, Rickets, Hypocalcemia, Joint hypermobility, Thin bony cortex, Unconj...	OMIM:613658
Infantile Nephropathic Cystinosis	Hypokalemia, Abnormal blood ion concentration, Hypophosphatemia, Rickets	ORPHA:411629
Familial Multiple Lipomatosis	Hyperlipidemia	ORPHA:199276
Aapoaiv Amyloidosis	Elevated circulating creatinine concentration, Hyperlipidemia	ORPHA:439232
Wilson Disease	Hypouricemia, Hypoalbuminemia, Osteomalacia, Hyperbilirubinemia, Increased circulating copper con...	OMIM:277900
Carnitine Palmitoyl Transferase Ii Deficiency, Neonatal Form	Elevated circulating acylcarnitine concentration, Decreased plasma free carnitine, Hyperlipidemia...	ORPHA:228308
Lipodystrophy, Familial Partial, Type 7	Hypercholesterolemia, Hypertriglyceridemia	OMIM:606721
Anoctamin-5-Related Limb-Girdle Muscular Dystrophy R12	EMG: myotonic runs	ORPHA:206549
Schimke Immuno-Osseous Dysplasia	Hyperlipidemia	ORPHA:1830
Parenteral Nutrition-Associated Cholestasis	Hyperlipidemia, Conjugated hyperbilirubinemia, Abnormal circulating fatty-acid concentration	ORPHA:567983
Steinert Myotonic Dystrophy	Hypercholesterolemia	ORPHA:273
Bardet-Biedl Syndrome	Joint hypermobility, Hypertriglyceridemia, Decreased HDL cholesterol concentration	ORPHA:110
Cystinosis, Nephropathic	Decreased circulating carnitine concentration, Rickets, Hypomagnesemia, Hypophosphatemic rickets,...	OMIM:219800
Occipital Horn Syndrome	Synostosis of joints, Osteopenia, Rickets, Osteomalacia, Joint hypermobility, Osteoporosis, Osteo...	ORPHA:198
Wiedemann-Rautenstrauch Syndrome	Osteopenia, Camptodactyly of finger, Joint hypermobility, Synovitis, Hypertriglyceridemia	ORPHA:3455
Wiedemann-Rautenstrauch Syndrome	Flexion contracture, Hypertriglyceridemia	OMIM:264090
Glycogen Storage Disease Ic	Xanthelasma, Gout, Hyperlipidemia, Hyperuricemia	OMIM:232240
Hypomagnesemia 3, Renal	Increased circulating beta-C-terminal telopeptide concentration, Hyperphosphatemia, Rickets, Hypo...	OMIM:248250
Biliary, Renal, Neurologic, And Skeletal Syndrome	Hypoalbuminemia, Osteopenia, Increased circulating ferritin concentration, Elevated circulating c...	OMIM:619534
Homozygous Familial Hypercholesterolemia	Hyperlipidemia, Increased LDL cholesterol concentration, Hypercholesterolemia	ORPHA:391665
Idiopathic Steroid-Sensitive Nephrotic Syndrome With Secondary Steroid Resistance	Hypoalbuminemia, Hyperlipidemia	ORPHA:567546
Immunodeficiency 82 With Systemic Inflammation	Hypoalbuminemia, Osteomalacia, Osteomyelitis, Arthritis, Elevated circulating C-reactive protein ...	OMIM:619381
Fabry Disease	Reduced bone mineral density, Hyperlipidemia, Arthritis, Abnormal circulating lipid concentration	ORPHA:324
Microcephalic Osteodysplastic Primordial Dwarfism Types I And Iii	Osteopenia, Rickets, Osteomalacia, Osteoporosis, Abnormally ossified vertebrae	ORPHA:2636
Primary Triglyceride Deposit Cardiomyovasculopathy	Hyperlipidemia, Elevated circulating creatine kinase concentration	ORPHA:565612
Woodhouse-Sakati Syndrome	Osteopenia, Hyperlipidemia	ORPHA:3464
Woodhouse-Sakati Syndrome	Hyperlipidemia	OMIM:241080
Generalized Arterial Calcification Of Infancy	Abnormal calcification of the carpal bones, Hypophosphatemic rickets, Fused cervical vertebrae, O...	ORPHA:51608
Rapid-Onset Childhood Obesity-Hypothalamic Dysfunction-Hypoventilation-Autonomic Dysregulation Syndrome	Hyponatremia, Hyperlipidemia	ORPHA:293987
Alström Syndrome	Hyperostosis frontalis interna, Hyperlipidemia, Hypertriglyceridemia	ORPHA:64

Histopathology

Summary table of phenotypes displayed during the Histopathology procedure which are considered significant. Full histopathology data table, including submitted images, can be accessed by clicking any row in this table.

There is no histopathology data for Rxrg

IMPC related publications

The table below lists publications which used either products generated by the IMPC or data produced by the phenotyping efforts of the IMPC. These publications have also been associated to Rxrg.

No publications found that use IMPC mice or data for Rxrg.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.

Sequence

Guides

Sequence	Guide sequence	pam	chr	start	stop	strand	Genome build	gRNA Concentration	Truncated Guide	Reversed	Sanger service	Guide format	Guide source

Nucleases

Nuclease type	Nuclease class

Genotype primers

Sequence	Name

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