Raf1 | v-raf-leukemia viral oncogene 1

GeneMGI:97847Synonyms: Craf1, v-Raf, +4 more

Physiological systems

19 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Vision/eye Mortality/aging

17 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

8Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:



preweaning lethality, complete penetrance	1 supporting dataset	Raf1^{tm1b(EUCOMM)Wtsi}	homozygote	Early adult	N/A ^*
abnormal lens morphology	1 supporting dataset	Raf1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.44x10^-6
cataract	1 supporting dataset	Raf1^{tm1b(EUCOMM)Wtsi}	heterozygote	Early adult	2.44x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Raf1.

Associated images

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Histopathology

There is no histopathology data found for Raf1.

IMPC related publications

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External links

No external links available for Raf1.

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*Raf1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell
*Raf1^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Raf1^{tm1b(EUCOMM)Wtsi}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse

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