Ptprd | protein tyrosine phosphatase receptor type D

GeneMGI:97812Synonyms: 1110002J03Rik, B230219D21Rik, +1 more

Physiological systems

18 / 24 physiological systems tested

8 Significantly impacted by the knock-out

Homeostasis/metabolism Immune system Adipose tissue Growth/size/body region Hematopoietic system Behavior/neurological Skeleton Mortality/aging

10 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased grip strength	3 supporting datasets	Ptprd^{tm2a(KOMP)Wtsi}	homozygote	Early adult	9.02x10^-8
decreased total body fat amount	1 supporting dataset	Ptprd^{tm2a(KOMP)Wtsi}	homozygote	Early adult	6.94x10^-5
improved glucose tolerance	1 supporting dataset	Ptprd^{tm2a(KOMP)Wtsi}	homozygote	Early adult	2.25x10^-5
increased leukocyte cell number	1 supporting dataset	Ptprd^{tm2a(KOMP)Wtsi}	homozygote	Early adult	6.54x10^-6
increased lean body mass	2 supporting datasets	Ptprd^{tm2a(KOMP)Wtsi}	homozygote	Early adult	2.67x10^-5
increased circulating iron level	1 supporting dataset	Ptprd^{tm2a(KOMP)Wtsi}	homozygote	Early adult	1.92x10^-5
increased bone mineral content	1 supporting dataset	Ptprd^{tm2a(KOMP)Wtsi}	homozygote	Early adult	7.24x10^-5
preweaning lethality, incomplete penetrance	1 supporting dataset	Ptprd^{tm2a(KOMP)Wtsi}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Ptprd.

Associated images

Loading...

Histopathology

There is no histopathology data found for Ptprd.

IMPC related publications

Loading...

External links

No external links available for Ptprd.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Ptprd^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Ptprd^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell mouse
*Ptprd^{tm2e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	es cell
*Ptprd^{tm470565(L1L2_GT0_LF2A_LacZ_BetactP_neo)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

My Genes