Serpine1 | serine (or cysteine) peptidase inhibitor, clade E, member 1

GeneMGI:97608Synonyms: PAI1, PAI-1, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Immune system Skeleton

15 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

3Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



enlarged lymph nodes	1 supporting dataset	Serpine1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*
abnormal sternum morphology	1 supporting dataset	Serpine1^em1(IMPC)Tcp	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Serpine1.

Associated images

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Histopathology

There is no histopathology data found for Serpine1.

IMPC related publications

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External links

No external links available for Serpine1.

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*Serpine1^em1(IMPC)Tcp*	Inter-exon deletion	‌	mouse
*Serpine1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Serpine1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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