Pkd1 | polycystin 1, transient receptor potential channel interacting
Physiological systems
19 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Immune system Hematopoietic system Mortality/aging
15 No significant impact
5 Not tested
Gene metrics:6Significant phenotypes
3Associated diseases
Expression examined in:46Adult tissues
42Embryo tissues
| decreased hematocrit | 1 supporting dataset | Pkd1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.84x10-6 | ||
| decreased circulating total protein level | 1 supporting dataset | Pkd1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 6.76x10-8 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Pkd1tm1b(EUCOMM)Hmgu | homozygote | Early adult | N/A * | ||
| increased neutrophil cell number | 2 supporting datasets | Pkd1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 4.02x10-6 | ||
| decreased erythrocyte cell number | 1 supporting dataset | Pkd1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 1.27x10-5 | ||
| decreased circulating alkaline phosphatase level | 1 supporting dataset | Pkd1tm1b(EUCOMM)Hmgu | heterozygote | Early adult | 3.74x10-8 |
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External links
No external links available for Pkd1.
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| Pkd1tm1(NCOM)Mfgc | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell |
| Pkd1tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell mouse |
| Pkd1tm1b(EUCOMM)Hmgu | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Pkd1tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |