Pax6 | paired box 6

GeneMGI:97490Synonyms: Gsfaey11, Pax-6, +4 more

Physiological systems

22 / 24 physiological systems tested

10 Significantly impacted by the knock-out

Embryo Growth/size/body region Digestive/alimentary Nervous system Vision/eye Liver/biliary system Behavior/neurological Craniofacial Cardiovascular system Mortality/aging

12 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:18Significant phenotypes

20Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal placenta vasculature	1 supporting dataset	Pax6^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
anophthalmia	1 supporting dataset	Pax6^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal eye morphology	2 supporting datasets	Pax6^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
abnormal liver morphology	1 supporting dataset	Pax6^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
cleft palate	1 supporting dataset	Pax6^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
anophthalmia	1 supporting dataset	Pax6^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
hyperactivity	4 supporting datasets	Pax6^em1(IMPC)Mbp	heterozygote	Early adult	1.53x10^-5
microphthalmia	2 supporting datasets	Pax6^em1(IMPC)Mbp	heterozygote	Early adult	N/A ^*
facial cleft	1 supporting dataset	Pax6^em1(IMPC)Mbp	homozygote	E15.5	N/A ^*
decreased body length	1 supporting dataset	Pax6^em1(IMPC)Mbp	heterozygote	Early adult	7.73x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

Rows per page:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Pax6.

Associated images

Loading...

Histopathology

There is no histopathology data found for Pax6.

IMPC related publications

Loading...

External links

No external links available for Pax6.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Pax6^em1(IMPC)Mbp*	Inter-exon deletion	‌	mouse
*Pax6^{tm119340(pL1L2_GT1_DelLacZ_bsd)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector
*Pax6^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell

My Genes