Pax4 | paired box 4

GeneMGI:97488Synonyms: Pax-4

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

Homeostasis/metabolism Behavior/neurological Mortality/aging

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:4Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

22Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased circulating alkaline phosphatase level	1 supporting dataset	Pax4^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	1.33x10^-5
tremors	1 supporting dataset	Pax4^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	3.14x10^-6
preweaning lethality, complete penetrance	1 supporting dataset	Pax4^{tm1b(EUCOMM)Hmgu}	homozygote	Early adult	N/A ^*
increased circulating total protein level	1 supporting dataset	Pax4^{tm1b(EUCOMM)Hmgu}	heterozygote	Early adult	5.13x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Pax4.

Associated images

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Histopathology

There is no histopathology data found for Pax4.

IMPC related publications

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External links

No external links available for Pax4.

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*Pax4^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Pax4^{tm1b(EUCOMM)Hmgu}*	Reporter-tagged deletion allele (with selection cassette)	‌	mouse
*Pax4^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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