Nfe2 | nuclear factor, erythroid derived 2

GeneMGI:97308Synonyms: NF-E2, p45, +2 more

Physiological systems

21 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Immune system Vision/eye Hematopoietic system Skeleton Craniofacial

16 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal spleen morphology	2 supporting datasets	Nfe2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
vertebral transformation	1 supporting dataset	Nfe2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	4.31x10^-5
abnormal vertebral arch morphology	1 supporting dataset	Nfe2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	6.91x10^-5
abnormal rib morphology	1 supporting dataset	Nfe2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	3.79x10^-5
abnormal cranium morphology	1 supporting dataset	Nfe2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	1.76x10^-6
abnormal cornea morphology	1 supporting dataset	Nfe2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	2.65x10^-5
rib fusion	1 supporting dataset	Nfe2^{em1(IMPC)Ccpcz}	heterozygote	Early adult	1.94x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Nfe2.

Associated images

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Histopathology

There is no histopathology data found for Nfe2.

IMPC related publications

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External links

No external links available for Nfe2.

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*Nfe2^{em1(IMPC)Ccpcz}*	Intra-exon deletion	‌	mouse
*Nfe2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell
*Nfe2^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Nfe2^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell
*Nfe2^{tm2a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Nfe2^{tm2e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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