Msx1 | msh homeobox 1
Physiological systems
20 / 24 physiological systems tested
7 Significantly impacted by the knock-out
Homeostasis/metabolism Growth/size/body region Digestive/alimentary Behavior/neurological Craniofacial Mortality/aging Cardiovascular system
13 No significant impact
4 Not tested
Data collections
Gene metrics:7Significant phenotypes
8Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues
| abnormal facial morphology | 1 supporting dataset | Msx1tm1b(KOMP)Wtsi | homozygote | E18.5 | N/A * | ||
| decreased thigmotaxis | 2 supporting datasets | Msx1tm1b(KOMP)Wtsi | heterozygote | Early adult | 5.99x10-5 | ||
| increased heart weight | 1 supporting dataset | Msx1tm1b(KOMP)Wtsi | heterozygote | Early adult | 1.11x10-5 | ||
| cleft palate | 1 supporting dataset | Msx1tm1b(KOMP)Wtsi | homozygote | E18.5 | N/A * | ||
| cyanosis | 1 supporting dataset | Msx1tm1b(KOMP)Wtsi | homozygote | E18.5 | N/A * | ||
| increased circulating free fatty acids level | 1 supporting dataset | Msx1tm1b(KOMP)Wtsi | heterozygote | Early adult | 3.77x10-5 | ||
| preweaning lethality, complete penetrance | 1 supporting dataset | Msx1tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * |
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External links
No external links available for Msx1.
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| Msx1tm1(KOMP)Vlcg | Reporter-tagged deletion allele (with selection cassette) | | es cell |
| Msx1tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Msx1tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |