Mdk | midkine
Physiological systems
18 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system Behavior/neurological Mortality/aging
14 No significant impact
6 Not tested
Data collections
Gene metrics:7Significant phenotypes
0Associated diseases
Expression examined in:48Adult tissues
46Embryo tissues
| impaired righting response | 1 supporting dataset | Mdktm1.1(KOMP)Mbp | homozygote | Early adult | 1.1x10-6 | ||
| decreased mean corpuscular volume | 1 supporting dataset | Mdktm1.1(KOMP)Mbp | homozygote | Early adult | 9.08x10-5 | ||
| increased circulating cholesterol level | 1 supporting dataset | Mdktm1.1(KOMP)Mbp | homozygote | Early adult | 1.05x10-5 | ||
| increased circulating sodium level | 1 supporting dataset | Mdktm1.1(KOMP)Mbp | heterozygote | Early adult | 3.7x10-7 | ||
| increased circulating HDL cholesterol level | 1 supporting dataset | Mdktm1.1(KOMP)Mbp | homozygote | Early adult | 1.84x10-7 | ||
| increased circulating chloride level | 1 supporting dataset | Mdktm1.1(KOMP)Mbp | heterozygote | Early adult | 1.04x10-5 | ||
| preweaning lethality, incomplete penetrance | 1 supporting dataset | Mdktm1.1(KOMP)Mbp | homozygote | Early adult | N/A * |
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External links
No external links available for Mdk.
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| Mdktm1(KOMP)Mbp | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell mouse |
| Mdktm1.1(KOMP)Mbp | Reporter-tagged deletion allele (post Cre, with no selection cassette) | | mouse |
| Mdktm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Mdktm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |