Il1r2 | interleukin 1 receptor, type II

GeneMGI:96546Synonyms: IL-1 receptor beta chain, CD121b, +1 more

Physiological systems

22 / 24 physiological systems tested

2 Significantly impacted by the knock-out

Hearing/vestibular/ear Behavior/neurological

20 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:2Significant phenotypes

0Associated diseases

Expression examined in:73Adult tissues

0Embryo tissues

Phenotypes

Allele:

Phy. System:



increased grip strength	2 supporting datasets	Il1r2^{tm1a(EUCOMM)Wtsi}	homozygote	Early adult	1.56x10^-8
abnormal auditory brainstem response	1 supporting dataset	Il1r2^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	2.9x10^-6

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Il1r2.

Associated images

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Histopathology

There is no histopathology data found for Il1r2.

IMPC related publications

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External links

No external links available for Il1r2.

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*Il1r2^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	ES Cell mouse
*Il1r2^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Il1r2^{tm1a(EUCOMM)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell mouse
*Il1r2^{tm1e(EUCOMM)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell

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