Irf8 | interferon regulatory factor 8
Physiological systems
17 / 24 physiological systems tested
2 Significantly impacted by the knock-out
Homeostasis/metabolism Hematopoietic system
15 No significant impact
7 Not tested
Data collections
Gene metrics:8Significant phenotypes
3Associated diseases
Expression examined in:49Adult tissues
50Embryo tissues
| decreased circulating free fatty acids level | 1 supporting dataset | Irf8tm1b(KOMP)Wtsi | homozygote | Early adult | 5.4x10-5 | ||
| increased mean corpuscular hemoglobin | 1 supporting dataset | Irf8tm1b(KOMP)Wtsi | homozygote | Early adult | 4.3x10-10 | ||
| decreased erythrocyte cell number | 1 supporting dataset | Irf8tm1b(KOMP)Wtsi | homozygote | Early adult | 7.32x10-5 | ||
| increased circulating total protein level | 1 supporting dataset | Irf8tm1b(KOMP)Wtsi | homozygote | Early adult | 2.85x10-6 | ||
| increased circulating sodium level | 1 supporting dataset | Irf8tm1b(KOMP)Wtsi | homozygote | Early adult | 2.4x10-5 | ||
| thrombocytopenia | 1 supporting dataset | Irf8tm1b(KOMP)Wtsi | homozygote | Early adult | 4.39x10-12 | ||
| increased mean corpuscular volume | 1 supporting dataset | Irf8tm1b(KOMP)Wtsi | homozygote | Early adult | 3.56x10-6 | ||
| decreased fasting circulating glucose level | 1 supporting dataset | Irf8tm1b(KOMP)Wtsi | homozygote | Early adult | 9.45x10-6 |
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External links
No external links available for Irf8.
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| Irf8tm1a(KOMP)Wtsi | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector es cell mouse |
| Irf8tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Irf8tm1e(KOMP)Wtsi | Targeted, non-conditional allele | | es cell |
| Irf8tm240291(L1L2_Bact_P) | Reporter-tagged deletion allele (with selection cassette) | | targeting vector |