Fshr | follicle stimulating hormone receptor

GeneMGI:95583Synonyms: follicle-stimulating hormone receptor, FSH-R, +1 more

Physiological systems

15 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Homeostasis/metabolism Pigmentation Adipose tissue Growth/size/body region Vision/eye Behavior/neurological Skeleton

8 No significant impact

9 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:7Significant phenotypes

4Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



decreased lean body mass	1 supporting dataset	Fshr^{tm1(KOMP)Vlcg}	homozygote	Early adult	8.46x10^-8
abnormal startle reflex	1 supporting dataset	Fshr^{tm1(KOMP)Vlcg}	homozygote	Early adult	9.45x10^-5
increased total body fat amount	2 supporting datasets	Fshr^{tm1(KOMP)Vlcg}	homozygote	Early adult	1.25x10^-7
decreased bone mineral content	2 supporting datasets	Fshr^{tm1(KOMP)Vlcg}	homozygote	Early adult	1.98x10^-11
decreased bone mineral density	1 supporting dataset	Fshr^{tm1(KOMP)Vlcg}	homozygote	Early adult	2.3x10^-5
abnormal iris pigmentation	1 supporting dataset	Fshr^{tm1(KOMP)Vlcg}	homozygote	Early adult	9.81x10^-5
increased fasting circulating glucose level	1 supporting dataset	Fshr^{tm1(KOMP)Vlcg}	homozygote	Early adult	2.9x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Fshr.

Associated images

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Histopathology

There is no histopathology data found for Fshr.

IMPC related publications

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External links

No external links available for Fshr.

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*Fshr^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell mouse
*Fshr^{tm371386(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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