Eif2b4 | eukaryotic translation initiation factor 2B, subunit 4 delta
Physiological systems
22 / 24 physiological systems tested
4 Significantly impacted by the knock-out
Embryo Growth/size/body region Vision/eye Mortality/aging
18 No significant impact
2 Not tested
Data collections
Gene metrics:5Significant phenotypes
6Associated diseases
Expression examined in:73Adult tissues
29Embryo tissues
| abnormal eye morphology | 1 supporting dataset | Eif2b4tm1b(KOMP)Wtsi | heterozygote | Early adult | N/A * | ||
| embryonic lethality prior to tooth bud stage | 1 supporting dataset | Eif2b4tm1b(KOMP)Wtsi | homozygote | E12.5 | N/A * | ||
| preweaning lethality, complete penetrance | 3 supporting datasets | Eif2b4tm1b(KOMP)Wtsi | homozygote | Early adult | N/A * | ||
| abnormal embryo size | 1 supporting dataset | Eif2b4tm1b(KOMP)Wtsi | heterozygote | E9.5 | N/A * | ||
| embryonic lethality prior to organogenesis | 1 supporting dataset | Eif2b4tm1b(KOMP)Wtsi | homozygote | E9.5 | N/A * |
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External links
No external links available for Eif2b4.
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| Eif2b4tm1(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | targeting vector ES Cell mouse |
| Eif2b4tm1a(EUCOMM)Hmgu | KO first allele (reporter-tagged insertion with conditional potential) | | targeting vector ES Cell |
| Eif2b4tm1b(KOMP)Wtsi | Reporter-tagged deletion allele (with selection cassette) | | mouse |
| Eif2b4tm1e(EUCOMM)Hmgu | Targeted, non-conditional allele | | ES Cell |