Bach1 | BTB and CNC homology 1, basic leucine zipper transcription factor 1

GeneMGI:894680Synonyms: 6230421P05Rik

Physiological systems

17 / 24 physiological systems tested

5 Significantly impacted by the knock-out

Homeostasis/metabolism Growth/size/body region Skeleton Cardiovascular system Mortality/aging

12 No significant impact

7 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:8Significant phenotypes

0Associated diseases

Expression examined in:49Adult tissues

46Embryo tissues

Phenotypes

Zygosity:

Phy. System:



increased bone mineral density	1 supporting dataset	Bach1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	8.33x10^-5
increased circulating sodium level	1 supporting dataset	Bach1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	2.45x10^-6
increased heart rate variability	1 supporting dataset	Bach1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	3.81x10^-6
cardiovascular system phenotype	1 supporting dataset	Bach1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	6.16x10^-8
increased heart weight	1 supporting dataset	Bach1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	5.24x10^-7
increased fasting circulating glucose level	1 supporting dataset	Bach1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.04x10^-16
preweaning lethality, incomplete penetrance	1 supporting dataset	Bach1^{tm1.1(KOMP)Vlcg}	homozygote	Early adult	N/A ^*
increased bone mineral content	1 supporting dataset	Bach1^{tm1.1(KOMP)Vlcg}	heterozygote	Early adult	1.83x10^-5

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Bach1.

Associated images

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Histopathology

There is no histopathology data found for Bach1.

IMPC related publications

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External links

No external links available for Bach1.

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*Bach1^{tm1(KOMP)Vlcg}*	Reporter-tagged deletion allele (with selection cassette)	‌	es cell mouse
*Bach1^{tm1(NCOM)Cmhd}*	Reporter-tagged deletion allele (with selection cassette)	‌	targeting vector es cell
*Bach1^{tm1.1(KOMP)Vlcg}*	Reporter-tagged deletion allele (post Cre, with no selection cassette)	‌	mouse
*Bach1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector es cell
*Bach1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	es cell

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