Calb1 | calbindin 1

GeneMGI:88248Synonyms: calbindin-D (28k), CB, +5 more

Physiological systems

22 / 24 physiological systems tested

9 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Muscle Vision/eye Hematopoietic system Skeleton Cardiovascular system

13 No significant impact

2 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:18Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



hydrometra	1 supporting dataset	Calb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thymus morphology	2 supporting datasets	Calb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged thymus	2 supporting datasets	Calb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
enlarged heart	2 supporting datasets	Calb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal heart morphology	2 supporting datasets	Calb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal vertebral arch morphology	2 supporting datasets	Calb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.27x10^-10
increased cardiac muscle contractility	2 supporting datasets	Calb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.69x10^-6
abnormal vertebrae morphology	1 supporting dataset	Calb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	3.17x10^-12
small spleen	1 supporting dataset	Calb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Calb1^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* This parameter was manually assessed for significance.

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lacZ Expression

No adult expression data available for Calb1.

Associated images

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Histopathology

There is no histopathology data found for Calb1.

IMPC related publications

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External links

No external links available for Calb1.

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*Calb1^{em1(IMPC)Ccpcz}*	Inter-exon deletion	‌	mouse
*Calb1^{tm1a(EUCOMM)Hmgu}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Calb1^{tm1e(EUCOMM)Hmgu}*	Targeted, non-conditional allele	‌	ES Cell

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