Alox5 | arachidonate 5-lipoxygenase

GeneMGI:87999Synonyms: 5-LOX, 5LX, +1 more

Physiological systems

18 / 24 physiological systems tested

4 Significantly impacted by the knock-out

Immune system Growth/size/body region Hematopoietic system Skeleton

14 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:3Significant phenotypes

1Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Phy. System:



abnormal spleen morphology	1 supporting dataset	Alox5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
abnormal thoracic cage shape	1 supporting dataset	Alox5^{em1(IMPC)Ccpcz}	homozygote	Early adult	1.52x10^-5
enlarged spleen	1 supporting dataset	Alox5^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

Download data as:

‌



‌	‌	‌	‌	‌	‌	‌	‌	‌	‌

* This parameter was manually assessed for significance.

Download data as:

lacZ Expression

No adult expression data available for Alox5.

Associated images

Loading...

Histopathology

There is no histopathology data found for Alox5.

IMPC related publications

Loading...

External links

No external links available for Alox5.

Order Mouse and ES Cells

All available products are supplied via our member's centres or partnerships. When ordering a product from the IMPC you will be redirected to one of their websites or prompted to start an email.



*Alox5^{em1(IMPC)Ccpcz}*	Exon Deletion	‌	mouse
*Alox5^{tm1a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell
*Alox5^{tm1e(KOMP)Wtsi}*	Targeted, non-conditional allele	‌	ES Cell
*Alox5^{tm2a(KOMP)Wtsi}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector ES Cell

My Genes