Gm5148 | predicted gene 5148

Physiological systems

21 / 24 physiological systems tested

7 Significantly impacted by the knock-out

Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Hematopoietic system Behavior/neurological Cardiovascular system

14 No significant impact

3 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data

Viability data
Body weight measurements
Embryo imaging data

Allele products available

Gene metrics:11Significant phenotypes

0Associated diseases

Expression examined in:0Adult tissues

0Embryo tissues

Phenotypes

Zygosity:

Phy. System:

Life Stage:



abnormal spleen morphology	1 supporting dataset	Gm5148^{em1(IMPC)Ccpcz}	homozygote	Early adult	N/A ^*
no spontaneous movement	1 supporting dataset	Gm5148^{em1(IMPC)Ccpcz}	homozygote	E18.5	N/A ^*
abnormal thymus morphology	2 supporting datasets	Gm5148^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
enlarged heart	1 supporting dataset	Gm5148^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal heart morphology	1 supporting dataset	Gm5148^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
enlarged thymus	2 supporting datasets	Gm5148^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
dilated aorta	1 supporting dataset	Gm5148^{em1(IMPC)Ccpcz}	heterozygote	Early adult	1.76x10^-5
enlarged spleen	1 supporting dataset	Gm5148^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal spleen morphology	1 supporting dataset	Gm5148^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*
abnormal testis morphology	1 supporting dataset	Gm5148^{em1(IMPC)Ccpcz}	heterozygote	Early adult	N/A ^*

* Does not have a P-value assigned because it was manually marked as significant.

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* Does not have a P-value assigned because it was manually marked as significant.

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lacZ Expression

No adult expression data available for Gm5148.

Associated images

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Histopathology

There is no histopathology data found for Gm5148.

IMPC related publications

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External links

No external links available for Gm5148.

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*Gm5148^{em1(IMPC)Ccpcz}*	Whole-gene deletion	‌	mouse
*Gm5148^{tm232903(L1L2_Bact_P)}*	KO first allele (reporter-tagged insertion with conditional potential)	‌	targeting vector

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