Mir124a-2 | microRNA 124a-2

GeneMGI:3618700Synonyms: mir-124a-2, mmu-mir-124-2, +2 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Vision/eye Behavior/neurological Mortality/aging

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

abnormal contextual conditioning behavior3 supporting datasetsMir124a-2tm1b(mirKO)WtsiheterozygoteEarly adult5.88x10-6 
decreased total retina thickness1 supporting datasetMir124a-2tm1b(mirKO)WtsiheterozygoteEarly adult4.85x10-5 
preweaning lethality, complete penetrance1 supporting datasetMir124a-2tm1b(mirKO)WtsihomozygoteEarly adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Mir124a-2tm1(mirKO)WtsiReporter-tagged deletion allele (with selection cassette)targeting vector
ES Cell
Mir124a-2tm1b(mirKO)WtsiReporter-tagged deletion allele (with selection cassette)mouse
Mir124a-2tm1d(mirKO)WtsiDeletion allele (post-Flp and Cre with no reporter)mouse

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