Gramd2a | GRAM domain containing 2A

GeneMGI:3528937Synonyms: Gramd2

Physiological systems

20 / 24 physiological systems tested

7 Significantly impacted by the knock-out

 Reproductive system Immune system Endocrine/exocrine gland Growth/size/body region Liver/biliary system Skeleton Renal/urinary system

13 No significant impact

4 Not tested

Gene metrics:6Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

enlarged urinary bladder1 supporting datasetGramd2aem1(IMPC)TcphomozygoteLate adultN/A * 
abnormal pancreas morphology1 supporting datasetGramd2aem1(IMPC)TcphomozygoteLate adultN/A * 
vertebral fusion1 supporting datasetGramd2aem1(IMPC)TcphomozygoteEarly adult6.14x10-5 
abnormal liver morphology1 supporting datasetGramd2aem1(IMPC)TcphomozygoteLate adultN/A * 
enlarged lymph nodes1 supporting datasetGramd2aem1(IMPC)TcphomozygoteEarly adultN/A * 
small uterus1 supporting datasetGramd2aem1(IMPC)TcphomozygoteLate adultN/A * 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Gramd2aem1(IMPC)TcpExon Deletionmouse
Gramd2atm1e(EUCOMM)WtsiTargeted, non-conditional allelees cell
Gramd2atm79352(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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