Exd1 | exonuclease 3'-5' domain containing 1

GeneMGI:3045306Synonyms: 4932702D22Rik, Exdl1

Physiological systems

18 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Growth/size/body region Hematopoietic system Cardiovascular system

15 No significant impact

6 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:3Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

decreased mean corpuscular hemoglobin concentration1 supporting datasetExd1tm1b(EUCOMM)HmguhomozygoteEarly adult2.78x10-8 
increased heart weight1 supporting datasetExd1tm1b(EUCOMM)HmguhomozygoteEarly adult7.81x10-6 
decreased mean corpuscular hemoglobin1 supporting datasetExd1tm1b(EUCOMM)HmguhomozygoteEarly adult2.51x10-7 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Exd1tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Exd1tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Exd1tm1e(EUCOMM)HmguTargeted, non-conditional alleleES Cell

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