Tox3 | TOX high mobility group box family member 3

GeneMGI:3039593Synonyms: Tnrc9, CAGF9, +1 more

Physiological systems

17 / 24 physiological systems tested

2 Significantly impacted by the knock-out

 Behavior/neurological Mortality/aging

15 No significant impact

7 Not tested

Gene metrics:2Significant phenotypes
0Associated diseases
Expression examined in:42Adult tissues
0Embryo tissues

Phenotypes

preweaning lethality, incomplete penetrance3 supporting datasetsTox3tm1b(KOMP)MbphomozygoteEarly adultN/A * 
decreased exploration in new environment1 supporting datasetTox3em1(IMPC)TcpheterozygoteEarly adult5.49x10-6 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Tox3em1(IMPC)MbpIndelmouse
Tox3em1(IMPC)TcpIndelmouse
Tox3tm1a(KOMP)MbpKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
mouse
Tox3tm1b(KOMP)MbpReporter-tagged deletion allele (with selection cassette)mouse
Tox3tm1e(KOMP)MbpTargeted, non-conditional alleleES Cell
Tox3tm1e(KOMP)WtsiTargeted, non-conditional alleleES Cell
Tox3tm2a(KOMP)WtsiKO first allele (reporter-tagged insertion with conditional potential)targeting vector
ES Cell
Tox3tm2e(KOMP)WtsiTargeted, non-conditional alleleES Cell

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