Cfap119 | cilia and flagella associated protein 119

GeneMGI:2685012Synonyms: LOC233899, Ccdc189, +1 more

Physiological systems

19 / 24 physiological systems tested

3 Significantly impacted by the knock-out

 Homeostasis/metabolism Reproductive system Behavior/neurological

16 No significant impact

5 Not tested

Data collections

LacZ expression
Histopathology
Images
How IMPC generates data
Gene metrics:5Significant phenotypes
0Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues

Phenotypes

male infertility1 supporting datasetCfap119tm1b(EUCOMM)HmguhomozygoteEarly adultN/A * 
increased circulating HDL cholesterol level1 supporting datasetCfap119tm1b(EUCOMM)HmguhomozygoteEarly adult2.78x10-8 
decreased locomotor activity3 supporting datasetsCfap119tm1b(EUCOMM)HmguhomozygoteEarly adult1.45x10-5 
decreased vertical activity1 supporting datasetCfap119tm1b(EUCOMM)HmguhomozygoteEarly adult7.85x10-5 
increased circulating cholesterol level1 supporting datasetCfap119tm1b(EUCOMM)HmguhomozygoteEarly adult7.81x10-9 
* Does not have a P-value assigned because it was manually marked as significant.
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* This parameter was manually assessed for significance.
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lacZ Expression

Associated images

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Histopathology

IMPC related publications

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Cfap119tm1a(EUCOMM)HmguKO first allele (reporter-tagged insertion with conditional potential)targeting vector
es cell
mouse
Cfap119tm1b(EUCOMM)HmguReporter-tagged deletion allele (with selection cassette)mouse
Cfap119tm1e(EUCOMM)HmguTargeted, non-conditional allelees cell
Cfap119tm83893(L1L2_Bact_P)KO first allele (reporter-tagged insertion with conditional potential)targeting vector

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