Slfn14 | schlafen 14
Physiological systems
18 / 24 physiological systems tested
3 Significantly impacted by the knock-out
Digestive/alimentary Vision/eye Hematopoietic system
15 No significant impact
6 Not tested
Data collections
Gene metrics:9Significant phenotypes
2Associated diseases
Expression examined in:0Adult tissues
0Embryo tissues
| increased mean platelet volume | 1 supporting dataset | Slfn14em1(IMPC)Tcp | homozygote | Early adult | 1.37x10-11 | ||
| decreased hematocrit | 1 supporting dataset | Slfn14em1(IMPC)Tcp | homozygote | Early adult | 4.89x10-6 | ||
| increased mean corpuscular hemoglobin concentration | 1 supporting dataset | Slfn14em1(IMPC)Tcp | homozygote | Early adult | 5.92x10-13 | ||
| increased mean corpuscular hemoglobin | 1 supporting dataset | Slfn14em1(IMPC)Tcp | homozygote | Early adult | 8.74x10-6 | ||
| cataract | 1 supporting dataset | Slfn14em1(IMPC)Tcp | homozygote | Early adult | 2.52x10-6 | ||
| decreased mean corpuscular volume | 1 supporting dataset | Slfn14em1(IMPC)Tcp | homozygote | Early adult | 7.22x10-10 | ||
| abnormal lens morphology | 1 supporting dataset | Slfn14em1(IMPC)Tcp | homozygote | Early adult | 1.5x10-6 | ||
| abnormal stomach morphology | 1 supporting dataset | Slfn14em1(IMPC)Tcp | homozygote | Early adult | N/A * | ||
| increased red blood cell distribution width | 1 supporting dataset | Slfn14em1(IMPC)Tcp | homozygote | Early adult | 1.17x10-7 |
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Human diseases caused by Slfn14 mutations
The analysis uses data from IMPC, along with published data on other mouse mutants, in comparison to human disease reports in OMIM, Orphanet, and DECIPHER.
Phenotype comparisons summarize the similarity of mouse phenotypes with human disease phenotypes.
External links
No external links available for Slfn14.
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| Slfn14em1(IMPC)Tcp | Inter-exon deletion | | mouse |